Chacín de Bonilla L, Guanipa N, Cano G
Instituto de Investigaciones Clínicas, Facultad de Medicina, Universidad del Zulia, Maracaibo, Venezuela.
Invest Clin. 1990;31(2):61-82.
The present paper reports three fatal cases of massive strongyloidiasis. Case 1. A 37-year-old woman with a record of arthropathy and corticosteroids treatment, died in shock. The postmortem examination showed massive intestinal strongyloidiasis with larvae dissemination to lungs, liver, spleen and the adipose tissue located around adrenal glands. Case 2. A 12-year-old, malnourished girl died of peritonitis. The autopsy findings were lithiasis and perforation of jejunum, hyperinfectious strongyloidiasis of intestines and lungs, acute and chronic peritonitis. Case 3. A 7-year-old, cachectic girl with corticosteroid therapy, died in cardiorespiratory arrest. The autopsy revealed hyperinfection by S. stercoralis affecting stomach, intestines, lungs, liver and brain. In Venezuela, literature on massive strongyloidiasis is scarce. The present report stresses the importance of considering this syndrome in patients at risk, in endemic areas, like Venezuela, to prevent unnecessary deaths.
本文报告了三例严重类圆线虫病致死病例。病例1:一名37岁女性,有患关节病及接受皮质类固醇治疗史,死于休克。尸检显示肠道有大量类圆线虫,幼虫扩散至肺、肝、脾及肾上腺周围的脂肪组织。病例2:一名12岁营养不良女孩死于腹膜炎。尸检结果为空肠结石及穿孔、肠道和肺部的重度感染性类圆线虫病、急慢性腹膜炎。病例3:一名7岁消瘦女孩,接受皮质类固醇治疗,死于心肺骤停。尸检显示粪类圆线虫重度感染,累及胃、肠、肺、肝和脑。在委内瑞拉,关于严重类圆线虫病的文献很少。本报告强调,在委内瑞拉等流行地区,对于有风险的患者考虑这一综合征以预防不必要死亡的重要性。