Gjedde A, Evans A C
Can Dis Wkly Rep. 1990 Sep;16 Suppl 1E:105-9.
We used positron emission tomography to measure hippocampal and medial temporal lobe metabolism in brains of patients intoxicated by domoic acid from Prince Edward Island mussels. This analog of kainic acid specifically excites certain neurons in the hippocampus, and the study revealed a severe reduction of glucose metabolism in this part of the brain which paralleled the absence of long-, medium-, or short-term memory in these patients.
我们使用正电子发射断层扫描技术来测量因食用爱德华王子岛贻贝中的软骨藻酸而中毒的患者大脑中的海马体和内侧颞叶代谢情况。这种 kainic 酸的类似物会特异性地刺激海马体中的某些神经元，研究显示大脑这一部分的葡萄糖代谢严重降低，这与这些患者缺乏长、中、短期记忆的情况相一致。
