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用γ相机进行的133Xe(氙)肺通气与灌注研究

[133Xe (xenon) study of pulmonary ventilation and perfusion with a gamma camera].

作者信息

Khadzhikostova Kh, Sheĭretova E

出版信息

Khirurgiia (Sofiia). 1990;43(6):1-4.

PMID:2102502
Abstract

Pulmonary ventilation and perfusion on regional level was measured by determining the distribution and elimination of introduced by inhalation 133He-gas, accordingly of intravenously injected 133He-solution. Fifty seven patients 7 to 60 years of age were included in the study, distributed by diagnoses, as follows: pulmonary thromboembolism 24 patients, 16 children with recurrent bronchopneumonia, pneumonia 10, central lung cancer 4, lung echinococcus 2 and one patient with LTE associated with chronic obstructive lung disease. All had ventilatory and subsequent perfusion dynamic scintigraphy. Ventilation was measured by the single breath technique. Perfusion scintigraphy was performed by the foregoing scheme, but by intravenous injection of 133He-solution. The entry, distribution and elimination of 133He-solution. The entry, distribution and elimination of 133He-gas and accordingly 133He-solution were followed up on gamma-camera display, and the time of radioactive gas elimination from the lungs was determined. Being practicable and nontraumatic, ventilation and perfusion scintigraphy may be repeated several times. This fact helps to follow up the evolution of the disease and the effect of conservative or surgical treatment. The results give an idea of the topographic and functional diagnosis of lung diseases.

摘要

通过测定吸入的133氖气以及静脉注射的133氖溶液的分布和清除情况,来测量区域水平的肺通气和灌注。本研究纳入了57例7至60岁的患者,按诊断分类如下:肺血栓栓塞症24例,复发性支气管肺炎患儿16例,肺炎10例,中心型肺癌4例,肺包虫病2例,以及1例与慢性阻塞性肺疾病相关的局限性肺炎。所有患者均接受了通气及后续的灌注动态闪烁扫描。通气通过单次呼吸技术进行测量。灌注闪烁扫描按照上述方案进行,但通过静脉注射133氖溶液。跟踪133氖溶液的进入、分布和清除情况。在γ相机显示屏上跟踪133氖气以及相应的133氖溶液的进入、分布和清除情况,并确定放射性气体从肺部清除的时间。通气和灌注闪烁扫描可行且无创,可以重复进行多次。这一事实有助于跟踪疾病的进展以及保守或手术治疗的效果。结果为肺部疾病的地形学和功能诊断提供了思路。

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