Taillefer R, Jadliwalla M, Pellerin E, Lafontaine E, Duranceau A
Department of Nuclear Medicine, Université de Montréal, Canada.
J Nucl Med. 1990 Dec;31(12):1921-6.
Radionuclide esophageal transit study (RETS) has been developed to assess motor function of the esophagus. The purpose of this study was to compare RETS to esophageal motility studies (EMS) in detection of motility disorders. A total of 109 consecutive patients without previous history of surgery on the esophagus underwent both RETS and EMS within one month of each other. Final diagnosis was divided into three categories: I--primary esophageal motor disorders (n = 39); II--reflux disease (n = 48); and III--non-cardiac chest pain and/or dysphagia (n = 22). Using EMS as the standard, the results of RETS were as follows: sensitivity for detection of motor dysfunction was 97%, 92%, and 77% for Groups I, II, and III, respectively, while specificity was 91% for Group II and 100% for Group III. Global sensitivity was 92% and specificity was 88%. No clinically significant motor disorders were missed by RETS. In conclusion, RETS is a useful noninvasive test for the screening of patients with symptoms thought to be of esophageal origin.
放射性核素食管通过时间研究（RETS）已被用于评估食管的运动功能。本研究的目的是比较RETS与食管动力研究（EMS）在检测动力障碍方面的差异。共有109例既往无食管手术史的连续患者在彼此间隔一个月内分别接受了RETS和EMS检查。最终诊断分为三类：I类——原发性食管动力障碍（n = 39）；II类——反流性疾病（n = 48）；III类——非心源性胸痛和/或吞咽困难（n = 22）。以EMS作为标准，RETS的结果如下：I、II、III组检测运动功能障碍的敏感性分别为97%、92%和77%，而II组的特异性为91%，III组为100%。总体敏感性为92%，特异性为88%。RETS未漏诊任何具有临床意义的运动障碍。总之，RETS是一种用于筛查疑似食管源性症状患者的有用的无创检查。
