Bear R, Goldstein M, Phillipson E, Ho M, Hammeke M, Feldman R, Handelsman S, Halperin M
Can Med Assoc J. 1977 Oct 22;117(8):900-3.
Eleven instances of a mixed acid-base disorder consisting of chronic respiratory acidosis and metabolic alkalosis were recognized in eight patients with chronic obstructive lung disease and carbon dioxide retention. Correction of the metabolic alkalosis led to substantial improvement in blood gas values and clinical symptoms. Patients with mixed chronic respiratory acidosis and metabolic alkalosis constitute a common subgroup of patients with chronic obstructive lung disease and carbon dioxide retention; these patients benefit from correction of the metabolic alkalosis.
在8例患有慢性阻塞性肺疾病并伴有二氧化碳潴留的患者中，识别出11例由慢性呼吸性酸中毒和代谢性碱中毒组成的混合性酸碱紊乱病例。代谢性碱中毒的纠正使血气值和临床症状有了显著改善。患有慢性呼吸性酸中毒和代谢性碱中毒的混合病例构成了慢性阻塞性肺疾病并伴有二氧化碳潴留患者中的一个常见亚组；这些患者可从代谢性碱中毒的纠正中获益。
