代谢性碱中毒对慢性阻塞性肺疾病患者呼吸功能的影响。
Effect of metabolic alkalosis on respiratory function in patients with chronic obstructive lung disease.
作者信息
Bear R, Goldstein M, Phillipson E, Ho M, Hammeke M, Feldman R, Handelsman S, Halperin M
出版信息
Can Med Assoc J. 1977 Oct 22;117(8):900-3.
Abstract
Eleven instances of a mixed acid-base disorder consisting of chronic respiratory acidosis and metabolic alkalosis were recognized in eight patients with chronic obstructive lung disease and carbon dioxide retention. Correction of the metabolic alkalosis led to substantial improvement in blood gas values and clinical symptoms. Patients with mixed chronic respiratory acidosis and metabolic alkalosis constitute a common subgroup of patients with chronic obstructive lung disease and carbon dioxide retention; these patients benefit from correction of the metabolic alkalosis.
摘要
在8例患有慢性阻塞性肺疾病并伴有二氧化碳潴留的患者中，识别出11例由慢性呼吸性酸中毒和代谢性碱中毒组成的混合性酸碱紊乱病例。代谢性碱中毒的纠正使血气值和临床症状有了显著改善。患有慢性呼吸性酸中毒和代谢性碱中毒的混合病例构成了慢性阻塞性肺疾病并伴有二氧化碳潴留患者中的一个常见亚组；这些患者可从代谢性碱中毒的纠正中获益。
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本文引用的文献
1
Effects of the carbonic anhydrase inhibitor "6063" (diamox) on respiration and electrolyte metabolism of patients with respiratory acidosis.碳酸酐酶抑制剂“6063”（乙酰唑胺）对呼吸性酸中毒患者呼吸及电解质代谢的影响。
Am J Med. 1955 Apr;18(4):536-46. doi: 10.1016/0002-9343(55)90453-8.
2
ROLE OF CEREBRAL FLUIDS IN CONTROL OF RESPIRATION AS STUDIED IN UNANESTHETIZED GOATS.在未麻醉山羊中研究脑脊液在呼吸控制中的作用
Am J Physiol. 1965 Mar;208:436-50. doi: 10.1152/ajplegacy.1965.208.3.436.
3
THE RESPONSE OF EXTRACELLULAR HYDROGEN ION CONCENTRATION TO GRADED DEGREES OF CHRONIC HYPERCAPNIA: THE PHYSIOLOGIC LIMITS OF THE DEFENSE OF PH.细胞外氢离子浓度对不同程度慢性高碳酸血症的反应：pH 防御的生理极限
J Clin Invest. 1965 Feb;44(2):291-301. doi: 10.1172/JCI105143.
4
Abnormalities of acid-base regulation in chronic pulmonary disease, with special reference to hypercapnia and extracellular alkalosis.
N Engl J Med. 1963 Apr 25;268:917-22. doi: 10.1056/NEJM196304252681703.
5
The treatment of respiratory acidosis with a potent carbonic anhydrase inhibitor (dichlorphenamide).用强效碳酸酐酶抑制剂（二氯苯磺胺）治疗呼吸性酸中毒。
Am J Med Sci. 1958 Nov;236(5):603-9.
6
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Clin Sci. 1957 Aug;16(3):413-20.
7
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9
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