立体定向¹⁸⁶铼腔内照射治疗囊性颅咽管瘤的疗效
[Curative effect of stereotactic 186Re endocavitary irradiation on cystic craniopharyngioma].
作者信息
Guo Chuan-jun, Wang Yan-chun, Zhou Zhen-hu, Zhu Jian-xin, Li Zhong-min, Guo Chang-li
机构信息
Department of Neurosurgery, Liaocheng People's Hospital, Liaocheng 252000, China.
出版信息
Zhonghua Zhong Liu Za Zhi. 2010 Jul;32(7):548-50.
OBJECTIVE
To evaluate the treatment results of stereotactic (186)Re intracavitary irradiation in the patients with craniopharyngioma.
METHODS
Nineteen patients were treated with stereotactic (186)Re intracavitary irradiation, including 12 males and 7 females (average age, 37.2 years). Among them 12 patients had a solitary cyst, whereas 7 patients with mixed structure (e.g., a large cyst with a small solid portion). The mean volume of the cystic portion of the tumor before irradiation was 8390 mm(3).
RESULTS
The patients were followed up for 6 months to 3 years. The retraction of the cyst was complete in 7 patients, cyst volume decreased more than 50% in 5 patients and less than 50% in 7 cases. Among the 8 patients with visual acuity deficit before irradiation, 5 were improved. No hypopituitarism occurred in patients with normal pituitary function before treatment. One of the 4 patients with hypopituitarism was improved, 3 of the 5 patients with diabetes insipidus was improved.
CONCLUSION
Stereotactic (186)Re endocavitary irradiation for the treatment of cystic craniopharyngioma is a safe and effective procedure.
目的
评估立体定向（186）铼腔内照射治疗颅咽管瘤患者的疗效。
方法
19例患者接受了立体定向（186）铼腔内照射治疗，其中男性12例，女性7例（平均年龄37.2岁）。其中12例患者有单个囊肿，7例患者为混合结构（如大囊肿伴有小的实性部分）。照射前肿瘤囊性部分的平均体积为8390立方毫米。
结果
患者随访6个月至3年。7例患者囊肿完全回缩，5例患者囊肿体积缩小超过50%，7例患者囊肿体积缩小不到50%。照射前有视力缺陷的8例患者中，5例有所改善。治疗前垂体功能正常的患者未发生垂体功能减退。4例垂体功能减退患者中有1例有所改善，5例尿崩症患者中有3例有所改善。
结论
立体定向（186）铼腔内照射治疗囊性颅咽管瘤是一种安全有效的方法。
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