Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, Utah, USA.
J Cataract Refract Surg. 2010 Nov;36(11):1925-33. doi: 10.1016/j.jcrs.2010.05.027.
To compare the incidence of flap complications after creation of laser in situ keratomileusis (LASIK) flaps using a zero-compression microkeratome or a femtosecond laser.
John A. Moran Eye Center, Department of Ophthalmology, University of Utah, Salt Lake City, Utah, USA.
Evidence-based manuscript.
The flap complication rate was evaluated during the initial 18 months of experience using a zero-compression microkeratome (Hansatome) or a femtosecond laser (IntraLase FS60) for flap creation.
The flap complication rate was 14.2% in the microkeratome group and 15.2% in the femtosecond laser group (P = .5437). The intraoperative flap complication rate was 5.3% and 2.9%, respectively (P = .0111), and the postoperative flap complication rate, 8.9% and 12.3%, respectively (P = .0201). The most common intraoperative complication in the microkeratome group was major epithelial defect/sloughing; the rate (2.6%) was statistically significantly higher than in the femtosecond laser group (P = .0006). The most common postoperative complication in both groups was diffuse lamellar keratitis (DLK) (6.0%, microkeratome; 10.6%, femtosecond laser) (P = .0002).
Although the total complication rates between the 2 groups were similar, the microkeratome group had significantly more epithelial defects intraoperatively and the femtosecond laser group had significantly more DLK cases postoperatively.
比较使用零压微角膜刀和飞秒激光制作准分子激光原位角膜磨镶术（LASIK）瓣后瓣并发症的发生率。
美国犹他州盐湖城犹他大学约翰·A·莫兰眼科中心，眼科。
基于证据的文稿。
使用零压微角膜刀（Hansatome）或飞秒激光（IntraLase FS60）制作瓣，评估初始 18 个月经验中的瓣并发症发生率。
微角膜刀组瓣并发症发生率为 14.2%，飞秒激光组为 15.2%（P =.5437）。术中瓣并发症发生率分别为 5.3%和 2.9%（P =.0111），术后瓣并发症发生率分别为 8.9%和 12.3%（P =.0201）。微角膜刀组术中最常见的并发症是主要上皮缺损/脱落；发生率（2.6%）明显高于飞秒激光组（P =.0006）。两组中最常见的术后并发症均为弥漫性层间角膜炎（DLK）（6.0%，微角膜刀；10.6%，飞秒激光）（P =.0002）。
尽管两组的总并发症发生率相似，但微角膜刀组术中上皮缺损明显更多，飞秒激光组术后 DLK 病例明显更多。
