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ST 段抬高型心肌梗死患者经院前激活心脏导管术团队对治疗时间的影响。

The impact of prehospital activation of the cardiac catheterization team on time to treatment for patients presenting with ST-segment-elevation myocardial infarction.

机构信息

Department of Emergency Medicine, Virginia Commonwealth University Medical Center, Richmond, VA 23298, USA.

出版信息

Am J Emerg Med. 2011 Nov;29(9):1117-24. doi: 10.1016/j.ajem.2010.08.005. Epub 2010 Oct 27.

Abstract

OBJECTIVE

We sought to evaluate the accuracy of emergency medical services (EMS) activation of the cardiac catheterization laboratory (CCL) for patients with ST-elevation myocardial infarction (STEMI) and its impact on treatment intervals from dispatch to reperfusion.

METHODS

We conducted a before-and-after cohort study of patients presenting via EMS with prehospital electrocardiogram findings consistent with STEMI. Before August 20, 2007, percutaneous coronary intervention was initiated after patient arrival. Afterward, EMS providers could activate the CCL if the prehospital electrocardiogram automated interpretation indicated STEMI. All interval times from EMS dispatch to percutaneous coronary intervention were measured via synchronized timepieces.

RESULTS

A total of 53 patients, 14 before and 39 after prehospital activation, were included. Emergency medical services CCL activation was 79.6% sensitive (95% confidence interval [CI], 65.2%-89.3%) and 99.7% specific (95% CI, 99.1%-99.9%). Mean door-to-hospital electrocardiogram and mean CCL-to-reperfusion times were unaffected by the intervention. Prehospital activation of the CCL significantly improved mean door-to-balloon (D2B) time by 18.2 minutes (95% CI, 7.69-28.71 minutes; P = .0029) and door-to-CCL by 14.8 minutes (95% CI, 6.20-23.39 minutes; P = .0024). Improvements in D2B were independent of presentation during peak hours (F ratio = 17.02, P < .0001). There were significant time savings reflected in all EMS intervals: 20.7 minutes (95% CI, 9.1-32.3 minutes; P = .0015) in mean dispatch-to-reperfusion time, 22.2 minutes (95% CI, 11.45-32.95 minutes; P = .0003) in mean first medical contact-to-reperfusion time, and 20 minutes (95% CI, 10.95-29.05 minutes; P = .0001) in recognition-to-reperfusion time.

CONCLUSIONS

Emergency medical service providers can appropriately activate the CCL for patients with STEMI before emergency department arrival, significantly reducing mean D2B time. Significant reduction is demonstrated throughout EMS intervals.

摘要

目的

我们旨在评估急诊医疗服务(EMS)激活心脏导管室(CCL)对 ST 段抬高型心肌梗死(STEMI)患者的准确性,以及其对从调度到再灌注治疗时间的影响。

方法

我们对通过 EMS 就诊且院前心电图检查结果符合 STEMI 的患者进行了一项前后队列研究。在 2007 年 8 月 20 日之前,患者到达后会进行经皮冠状动脉介入治疗。此后,如果院前心电图自动解读提示 STEMI,EMS 提供者可以激活 CCL。通过同步计时表测量从 EMS 调度到经皮冠状动脉介入治疗的所有时间间隔。

结果

共纳入 53 例患者,其中 14 例在院前激活前,39 例在院前激活后。EMS 激活 CCL 的敏感性为 79.6%(95%置信区间[CI],65.2%-89.3%),特异性为 99.7%(95% CI,99.1%-99.9%)。干预措施对门到医院心电图和 CCL 到再灌注的平均时间无影响。CCL 的院前激活使平均门到球囊(D2B)时间缩短 18.2 分钟(95%CI,7.69-28.71 分钟;P =.0029),门到 CCL 时间缩短 14.8 分钟(95%CI,6.20-23.39 分钟;P =.0024)。D2B 的改善与高峰期就诊无关(F 比=17.02,P <.0001)。所有 EMS 间隔时间均有显著的节省时间:从调度到再灌注的平均时间缩短 20.7 分钟(95%CI,9.1-32.3 分钟;P =.0015),从首次医疗接触到再灌注的平均时间缩短 22.2 分钟(95%CI,11.45-32.95 分钟;P =.0003),从识别到再灌注的平均时间缩短 20 分钟(95%CI,10.95-29.05 分钟;P =.0001)。

结论

EMS 提供者可以在患者到达急诊室之前适当地激活 CCL,从而显著缩短平均 D2B 时间。整个 EMS 间隔时间都显示出显著的缩短。

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