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[染色体浓缩变体与哺乳动物卵母细胞进一步发育能力的评估]

[Variants of chromosome compactization and the estimation of the capacity of mammalian oocytes for further development].

作者信息

Slozina N M, Ponomareva N A, Linskaia M N, Neronova E G, Nikitin A I

出版信息

Tsitologiia. 1990;32(12):1187-92.

PMID:2103079
Abstract

The morphology of chromatin in spontaneously ovulated rat's oocytes was investigated. The degree of chromatin condensation was shown to vary widely: along with the typical cytological picture of metaphase II, both highly condensed (clamped) and decondensed ("not typical") forms of chromosomes were observed. A direct relation was discovered between the prevalence of the not typical morphological forms of oocyte chromosomes and the level of embryonal death. The shape of clamped and decondensed forms increased in the oocytes from old rats and in post-ovulatory aged oocytes.

摘要

对自然排卵的大鼠卵母细胞中的染色质形态进行了研究。结果表明,染色质凝聚程度差异很大:除了典型的中期II细胞学图像外,还观察到高度凝聚(钳状)和解凝聚(“非典型”)形式的染色体。发现卵母细胞染色体非典型形态的普遍程度与胚胎死亡水平之间存在直接关系。老龄大鼠卵母细胞和排卵后老化卵母细胞中钳状和解凝聚形式的比例增加。

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