化疗成功治疗颈段脊髓毛黏液样星形细胞瘤：病例报告
Pilomyxoid astrocytoma of the cervical spinal cord successfully treated with chemotherapy: case report.
作者信息
Matsuzaki Kazuhito, Kageji Teruyoshi, Watanabe Hiroyoshi, Hirose Takanori, Nagahiro Shinji
机构信息
Department of Neurosurgery, Kawasaki Medical School, Kurashiki, Okayama, Japan.
出版信息
Neurol Med Chir (Tokyo). 2010;50(10):939-42. doi: 10.2176/nmc.50.939.
A 15-month-old girl presented with a spinal pilomyxoid astrocytoma manifesting as a 3-month history of dysphagia. Magnetic resonance imaging showed an intramedullary mass of the cervical spinal cord at C1-C6 with syringobulbia. She underwent partial removal of the tumor and received postoperative chemotherapy with cisplatin and etoposide. The tumor completely responded to the treatment and has not relapsed for 64 months. Pilomyxoid astrocytoma frequently occurs in the opticohypothalamic regions but is rare in the spine. The present case suggests that surgery followed by chemotherapy with cisplatin and etoposide may be an effective therapeutic option for pilomyxoid astrocytoma of the cervical spinal cord.
一名15个月大的女孩因吞咽困难3个月就诊，诊断为脊髓毛黏液样星形细胞瘤。磁共振成像显示颈髓C1 - C6节段髓内肿块并伴有延髓空洞症。她接受了肿瘤部分切除术，并在术后接受顺铂和依托泊苷化疗。肿瘤对治疗完全缓解，64个月未复发。毛黏液样星形细胞瘤常发生于视交叉下丘脑区域，但在脊柱中罕见。本病例提示，手术联合顺铂和依托泊苷化疗可能是颈髓毛黏液样星形细胞瘤的有效治疗选择。
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