Fukuda Hitoshi, Fukumitsu Ryu, Andoh Mitsushige, Suzuki Takayuki, Yamana Norikazu, Kataoka Hiroharu, Iwasaki Koichi
Department of Neurosurgery, National Hospital Organization Himeji Medical Center, Himeji, Hyogo, Japan.
Neurol Med Chir (Tokyo). 2010;50(10):953-5. doi: 10.2176/nmc.50.953.
A 45-year-old woman presented with a rare case of small isolated Onodi cell mucocele manifesting as unilateral chronic optic neuropathy. The patient complained of gradual visual disturbance of her left eye with no other neurological abnormalities. Neuroimaging examinations showed a small cystic lesion located in the left posterior ethmoid extending into the anterior clinoid process. Surgery via the pterional epidural approach revealed a cystic lesion containing mucinous fluid isolated in the anterior clinoid process. Total removal of the lesion combined with unroofing of the left optic canal resulted in relief of the patient's symptom. Histological examination showed the lesion was a mucocele. Based on the radiological and surgical findings together with the histological examination, the final diagnosis was Onodi cell mucocele. Such small Onodi cell mucocele can cause optic neuropathy but is extremely unusual.
一名45岁女性出现罕见的孤立性小奥诺德细胞黏液囊肿病例，表现为单侧慢性视神经病变。患者主诉左眼逐渐出现视力障碍，无其他神经异常。神经影像学检查显示左后筛窦有一个小囊性病变，延伸至前床突。经翼点硬膜外入路手术发现一个含有黏液性液体的囊性病变，孤立于前床突。病变完全切除并打开左侧视神经管后，患者症状缓解。组织学检查显示病变为黏液囊肿。根据影像学、手术结果及组织学检查，最终诊断为奥诺德细胞黏液囊肿。如此小的奥诺德细胞黏液囊肿可导致视神经病变，但极为罕见。
