Suppr超能文献

争议:辅助剂在男性型脱发管理中是否有作用?

Controversy: is there a role for adjuvants in the management of male pattern hair loss?

作者信息

Rajput Rajendrasingh J

机构信息

R R Institute, 201-A, Gasper Enclave, Ambedkar Road, Pali Hill Market, Bandra (W), Mumbai 400050, India.

出版信息

J Cutan Aesthet Surg. 2010 May;3(2):82-6. doi: 10.4103/0974-2077.69016.

Abstract

Patients with hair loss are seeking treatment at a younger age and during earlier stages. Not all need hair transplants. Because of the lack of assured management and the fear of side-effects, patients are turning to ineffective alternative remedies from self-claimed experts. In this report, we discuss the available treatment options and how best they can be used in combination to produce satisfactory results. The traditional approach consists of administration of drugs such as minoxidil and finasteride. We propose a hypothesis that nutritional supplements, 2% ketoconazole shampoo and low-level laser therapy along with finasteride 1 mg used once in 3 days with 2% minoxidil used everyday, given in a cyclical medicine program may be useful to manage hair loss and achieve new hair growth. The scientific rationale for such an approach is explained. The need for further studies to establish the efficacy of the regime is stressed upon.

摘要

脱发患者寻求治疗的年龄越来越小,且处于疾病早期阶段。并非所有患者都需要进行植发。由于缺乏可靠的治疗方法且担心副作用,患者开始求助于自称专家的无效替代疗法。在本报告中,我们讨论了现有的治疗选择以及如何最佳地联合使用这些方法以取得满意的效果。传统方法包括使用米诺地尔和非那雄胺等药物。我们提出一个假设,即营养补充剂、2%酮康唑洗发水、低水平激光疗法,以及每三天服用一次1毫克非那雄胺并每天使用2%米诺地尔,按照周期性药物方案给药,可能有助于治疗脱发并促进新头发生长。文中解释了这种方法的科学原理。强调了需要进一步研究以确定该方案的疗效。

相似文献

1
Controversy: is there a role for adjuvants in the management of male pattern hair loss?
J Cutan Aesthet Surg. 2010 May;3(2):82-6. doi: 10.4103/0974-2077.69016.
2
Comparative efficacy of various treatment regimens for androgenetic alopecia in men.
J Dermatol. 2002 Aug;29(8):489-98. doi: 10.1111/j.1346-8138.2002.tb00314.x.
4
A review of the treatment of male pattern hair loss.
Expert Opin Pharmacother. 2020 Apr;21(5):603-612. doi: 10.1080/14656566.2020.1721463. Epub 2020 Feb 17.
5
The effectiveness of treatments for androgenetic alopecia: A systematic review and meta-analysis.
J Am Acad Dermatol. 2017 Jul;77(1):136-141.e5. doi: 10.1016/j.jaad.2017.02.054. Epub 2017 Apr 7.
6
Guidelines for the diagnosis and treatment of male-pattern and female-pattern hair loss, 2017 version.
J Dermatol. 2018 Sep;45(9):1031-1043. doi: 10.1111/1346-8138.14470. Epub 2018 Jun 4.
8
Androgenetic alopecia: an evidence-based treatment update.
Am J Clin Dermatol. 2014 Jul;15(3):217-30. doi: 10.1007/s40257-014-0077-5.
9
Efficacy of non-surgical treatments for androgenetic alopecia: a systematic review and network meta-analysis.
J Eur Acad Dermatol Venereol. 2018 Dec;32(12):2112-2125. doi: 10.1111/jdv.15081. Epub 2018 Jul 11.
10
Finasteride: a review of its use in male pattern hair loss.
Drugs. 1999 Jan;57(1):111-26. doi: 10.2165/00003495-199957010-00014.

引用本文的文献

1
Overview and Algorithmic Approach to Management of Male and Female Pattern Hair Loss.
Indian J Plast Surg. 2021 Dec 14;54(4):416-421. doi: 10.1055/s-0041-1739256. eCollection 2021 Oct.
4
Female pattern alopecia: current perspectives.
Int J Womens Health. 2013 Aug 29;5:541-56. doi: 10.2147/IJWH.S49337.
5
Pilot Study of 15 Patients Receiving a New Treatment Regimen for Androgenic Alopecia: The Effects of Atopy on AGA.
ISRN Dermatol. 2011;2011:241953. doi: 10.5402/2011/241953. Epub 2011 Apr 11.

本文引用的文献

2
Big head? Bald head! Skull expansion: alternative model for the primary mechanism of AGA.
Med Hypotheses. 2009 Jan;72(1):23-8. doi: 10.1016/j.mehy.2008.07.048. Epub 2008 Sep 11.
3
Male pattern baldness: current treatments, future prospects.
Drug Discov Today. 2008 Sep;13(17-18):791-7. doi: 10.1016/j.drudis.2008.05.010. Epub 2008 Jul 24.
4
Premature senescence of balding dermal papilla cells in vitro is associated with p16(INK4a) expression.
J Invest Dermatol. 2008 May;128(5):1088-94. doi: 10.1038/sj.jid.5701147. Epub 2007 Nov 8.
5
The effect of tripeptide-copper complex on human hair growth in vitro.
Arch Pharm Res. 2007 Jul;30(7):834-9. doi: 10.1007/BF02978833.
6
Finasteride 5 mg and sexual side effects: how many of these are related to a nocebo phenomenon?
J Sex Med. 2007 Nov;4(6):1708-12. doi: 10.1111/j.1743-6109.2007.00563.x. Epub 2007 Jul 26.
7
Ga-As (808 nm) laser irradiation enhances ATP production in human neuronal cells in culture.
Photomed Laser Surg. 2007 Jun;25(3):180-2. doi: 10.1089/pho.2007.2064.
8
Low-level laser therapy enhances wound healing in diabetic rats: a comparison of different lasers.
Photomed Laser Surg. 2007 Apr;25(2):72-7. doi: 10.1089/pho.2006.1094.
9
The current role of laser/light sources in the treatment of male and female pattern hair loss.
J Cosmet Laser Ther. 2007 Mar;9(1):27-8. doi: 10.1080/14764170601134479.
10

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验