根据肿瘤位置分析 151 例连续胃黏膜下肿瘤。
Analysis of 151 consecutive gastric submucosal tumors according to tumor location.
机构信息
Division of Gastrointestinal Surgery, Department of Surgery, College of Medicine, The Catholic University of Korea, Seocho-gu, Seoul, Korea.
出版信息
J Surg Oncol. 2011 Jul 1;104(1):72-5. doi: 10.1002/jso.21771. Epub 2010 Oct 28.
BACKGROUND
The aim of the present study was to evaluate the histopathological characteristics of gastric submucosal tumors (SMTs) according to their location.
METHODS
A retrospective analysis of a prospective database of 151 consecutive patients who underwent surgery for gastric SMTs between 2001 and 2009 was performed.
RESULTS
Of 151 gastric SMTs, 100 (66.2%) were gastrointestinal stromal tumors, 21 (13.9%) were leiomyomas, and 30 (19.9%) were other benign tumors. Leiomyoma was the most common neoplasm at the cardia (55.2%; P < 0.05), and the incidence of endophytic cardia tumors was higher compared with other locations (65.5%; P < 0.05). SMTs located at the cardia were significantly smaller than those found in the upper third (2.6 ± 1.0 vs. 4.1 ± 3.0; P < 0.05) and middle third (2.6 ± 1.0 vs. 3.9 ± 3.3; P < 0.05) of the stomach.
CONCLUSIONS
The characteristics of gastric SMTs located at the cardia differ significantly from those of gastric SMTs located in other regions of the stomach. These findings suggest that treatment strategy should be tailored by the location of tumors.
背景
本研究旨在根据胃黏膜下肿瘤（SMT）的位置评估其组织病理学特征。
方法
对 2001 年至 2009 年间连续 151 例行胃 SMT 手术的患者前瞻性数据库进行回顾性分析。
结果
151 例胃 SMT 中，胃肠间质瘤 100 例（66.2%），平滑肌瘤 21 例（13.9%），其他良性肿瘤 30 例（19.9%）。平滑肌瘤是贲门最常见的肿瘤（55.2%；P<0.05），且贲门内生型肿瘤的发生率高于其他部位（65.5%；P<0.05）。位于贲门的 SMT 明显小于位于胃上部（2.6±1.0 比 4.1±3.0；P<0.05）和中部（2.6±1.0 比 3.9±3.3；P<0.05）的 SMT。
结论
贲门 SMT 的特征与胃其他部位的 SMT 有显著差异。这些发现提示治疗策略应根据肿瘤位置进行调整。
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