[Changes in phagocytosis of aerobic bacteria by neutrophils after exposure to subinhibitory concentrations of aztreonam and ciprofloxacin].

In the present research work we are performing a study on the effect of the antibiotic concentrations low minimal inhibitory concentration of aztreonam and ciprofloxacin on phagocytosis of aerobic bacteria by neutrophils (Enterococcus faecalis, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa). Both antibiotics induced an increased of phagocytosis by similar mechanisms. In our assay aztreonam and ciprofloxacin would not act directly on granulocyte but they would affect the bacteria increasing the opsonization and phagocytosis.