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[真性红细胞增多症的神经系统表现。24例分析及文献复习]

[Neurologic manifestations of polycythemia vera. Analysis of 24 cases and review of the literature].

作者信息

Corredoira Sánchez J C, González López M, Cortés Laiño J A, Gomara García S, Pérez Alvarez R, Casariego Vales B, López Alvarez M J, García Rodríguez J F

机构信息

Servicio de Medicina Interna y Hematología, Hospital Xeral de Lugo.

出版信息

An Med Interna. 1990 Feb;7(2):67-70.

PMID:2103237
Abstract

Neurological symptoms (NS) of 33 patients diagnosed as suffering from polycythemia vera (PV) are described. 24 of them (73%) had NS at some point in their evolution, the most frequent being related to blood hyperviscosity (headache 51%, dizziness 36%, paresthesias 30%, sight alterations 21%). 5 patients had ictus (15%) and there were no bleeding symptoms in the nervous system. There were no significant differences (p greater than 0.05) in age, sex; hematocrit, platelet or volume of packed red cells, between patients with NS and those without NS. A complete remission of NS was obtained reducing the hematocrit, except in ictus patients. We did not find mortality, as a result of NS.

摘要

本文描述了33例诊断为真性红细胞增多症(PV)患者的神经症状(NS)。其中24例(73%)在病程的某些阶段出现了NS,最常见的与血液高粘滞度有关(头痛51%、头晕36%、感觉异常30%、视力改变21%)。5例患者发生卒中(15%),神经系统无出血症状。有NS的患者与无NS的患者在年龄、性别、血细胞比容、血小板或红细胞压积方面无显著差异(p>0.05)。除卒中患者外,通过降低血细胞比容,NS得到了完全缓解。我们未发现因NS导致的死亡病例。

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