Romanova S G, Romanov V G, Serebrennikova G A, Shtil' A A
Biomed Khim. 2010 Jul-Aug;56(4):457-70.
The review is summarizes current information on biological activity and search of the antineoplastic mechanism of action of alkyl glycerolipids. Special attention is paid to following problems: selective ability phosphorus alkyl glycerolipids, antineoplastic activity, cytostatic and cytotoxic effects of edelfosine and its analogues. The review contains set of the data known for today from the literature, on the possible mechanism cytoyoxic actions of such connections.
本综述总结了关于烷基甘油脂质生物活性的当前信息以及对其抗肿瘤作用机制的研究。特别关注以下问题:磷烷基甘油脂质的选择能力、抗肿瘤活性、依地福新及其类似物的细胞抑制和细胞毒性作用。该综述包含了目前从文献中已知的关于此类化合物可能的细胞毒性作用机制的一系列数据。