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上消化道内镜检查前进行乙型和丙型肝炎病毒感染检测:为肝炎患者配备专用内镜和检查室的理由。

Testing for hepatitis B and C virus infection before upper gastrointestinal endoscopy: justification for dedicated endoscope and room for hepatitis patients.

作者信息

Gulsen Murat Taner, Beyazit Yavuz, Guclu Mustafa, Koklu Seyfettin

机构信息

Department of Gastroenterology, Gaziantep University School of Medicine, Gaziantep, Turkey.

出版信息

Hepatogastroenterology. 2010 Jul-Aug;57(101):797-800.

Abstract

BACKGROUND/AIMS: Endoscopic interventions have become a significant tool in the diagnosis and treatment of gastrointestinal disorders. In order to avoid transmission of associated diseases, cleaning and disinfection/sterilization procedures of endoscopes and accessories are crucial. Hepatitis B virus and Hepatitis C virus infections are among the most common viral infections globally and maintain their position as a serious public health problem.

METHODOLOGY

One thousand patients visiting our gastroenterology department were diagnosed and, except for cirrhosis, were enrolled in this study. For patients with HBsAg and Anti-HCV positive, Aspartate Aminotransferase, Alanine Aminotransferase, hemogram and prothrombin time were examined and ultrasonography was performed.

RESULTS

Five hundred and seventy three patients (57.3%) were female and 427 patients (42.7%) were male. Among 1000 patients in total, 39 patients were detected to have hepatitis (3.9%). Of these patients, 28 (2.8%) had HBsAg (+), 10 (1%) had Anti-HCV (+), 1 (0.1%) had both HBsAg (+) and Anti-HCV (+).

CONCLUSIONS

It would be beneficial to include a determination of hepatitis serology of patients prior to endoscopy in daily practice. In addition, like dialysis machines, there is a need for further studies evaluating the cost effectiveness of using separate endoscopy devices allocated to groups of patients with HBV, HCV or to those who do not carry hepatitis.

摘要

背景/目的:内镜干预已成为胃肠道疾病诊断和治疗的重要工具。为避免相关疾病的传播,内镜及附件的清洁和消毒/灭菌程序至关重要。乙型肝炎病毒和丙型肝炎病毒感染是全球最常见的病毒感染之一,仍是严重的公共卫生问题。

方法

对我院胃肠病科就诊的1000例患者进行诊断,除肝硬化患者外,纳入本研究。对HBsAg和抗HCV阳性患者,检测天冬氨酸转氨酶、丙氨酸转氨酶、血常规和凝血酶原时间,并进行超声检查。

结果

573例患者(57.3%)为女性,427例患者(42.7%)为男性。1000例患者中,39例(3.9%)检测出患有肝炎。其中,28例(2.8%)HBsAg阳性,10例(1%)抗HCV阳性,1例(0.1%)HBsAg和抗HCV均阳性。

结论

在日常实践中,在内镜检查前对患者进行肝炎血清学检测将是有益的。此外,与透析机一样,需要进一步研究评估为乙肝、丙肝患者或未感染肝炎患者群体分配单独内镜设备的成本效益。

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