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上消化道内镜检查前进行乙型和丙型肝炎病毒感染检测:为肝炎患者配备专用内镜和检查室的理由。

Testing for hepatitis B and C virus infection before upper gastrointestinal endoscopy: justification for dedicated endoscope and room for hepatitis patients.

作者信息

Gulsen Murat Taner, Beyazit Yavuz, Guclu Mustafa, Koklu Seyfettin

机构信息

Department of Gastroenterology, Gaziantep University School of Medicine, Gaziantep, Turkey.

出版信息

Hepatogastroenterology. 2010 Jul-Aug;57(101):797-800.

PMID:21033232
Abstract

BACKGROUND/AIMS: Endoscopic interventions have become a significant tool in the diagnosis and treatment of gastrointestinal disorders. In order to avoid transmission of associated diseases, cleaning and disinfection/sterilization procedures of endoscopes and accessories are crucial. Hepatitis B virus and Hepatitis C virus infections are among the most common viral infections globally and maintain their position as a serious public health problem.

METHODOLOGY

One thousand patients visiting our gastroenterology department were diagnosed and, except for cirrhosis, were enrolled in this study. For patients with HBsAg and Anti-HCV positive, Aspartate Aminotransferase, Alanine Aminotransferase, hemogram and prothrombin time were examined and ultrasonography was performed.

RESULTS

Five hundred and seventy three patients (57.3%) were female and 427 patients (42.7%) were male. Among 1000 patients in total, 39 patients were detected to have hepatitis (3.9%). Of these patients, 28 (2.8%) had HBsAg (+), 10 (1%) had Anti-HCV (+), 1 (0.1%) had both HBsAg (+) and Anti-HCV (+).

CONCLUSIONS

It would be beneficial to include a determination of hepatitis serology of patients prior to endoscopy in daily practice. In addition, like dialysis machines, there is a need for further studies evaluating the cost effectiveness of using separate endoscopy devices allocated to groups of patients with HBV, HCV or to those who do not carry hepatitis.

摘要

背景/目的:内镜干预已成为胃肠道疾病诊断和治疗的重要工具。为避免相关疾病的传播,内镜及附件的清洁和消毒/灭菌程序至关重要。乙型肝炎病毒和丙型肝炎病毒感染是全球最常见的病毒感染之一,仍是严重的公共卫生问题。

方法

对我院胃肠病科就诊的1000例患者进行诊断,除肝硬化患者外,纳入本研究。对HBsAg和抗HCV阳性患者,检测天冬氨酸转氨酶、丙氨酸转氨酶、血常规和凝血酶原时间,并进行超声检查。

结果

573例患者(57.3%)为女性,427例患者(42.7%)为男性。1000例患者中,39例(3.9%)检测出患有肝炎。其中,28例(2.8%)HBsAg阳性,10例(1%)抗HCV阳性,1例(0.1%)HBsAg和抗HCV均阳性。

结论

在日常实践中,在内镜检查前对患者进行肝炎血清学检测将是有益的。此外,与透析机一样,需要进一步研究评估为乙肝、丙肝患者或未感染肝炎患者群体分配单独内镜设备的成本效益。

相似文献

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Testing for hepatitis B and C virus infection before upper gastrointestinal endoscopy: justification for dedicated endoscope and room for hepatitis patients.上消化道内镜检查前进行乙型和丙型肝炎病毒感染检测:为肝炎患者配备专用内镜和检查室的理由。
Hepatogastroenterology. 2010 Jul-Aug;57(101):797-800.
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Health care-associated transmission of hepatitis B and C viruses in endoscopy units.内镜中心乙型肝炎和丙型肝炎病毒的医源性传播。
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Prospective study of cross-infection from upper-GI endoscopy in a hepatitis C-prevalent population.在丙型肝炎高发人群中对上消化道内镜检查交叉感染的前瞻性研究。
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Reprocessing in digestive endoscopy units in Lombardy: results of a regional survey.伦巴第地区消化内镜科室的再处理:一项区域调查结果
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The microbial flora of the gastrointestinal tract and the cleaning of flexible endoscopes.胃肠道的微生物菌群与软性内镜的清洁
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Cleaning and disinfection of equipment for gastrointestinal endoscopy. Report of a Working Party of the British Society of Gastroenterology Endoscopy Committee.胃肠内镜设备的清洁与消毒。英国胃肠病学会内镜委员会工作组报告
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Effectiveness of manual cleaning and disinfection for the elimination of hepatitis C virus from GI endoscopes.手工清洗和消毒对消除胃肠内镜上丙型肝炎病毒的效果。
Am J Gastroenterol. 2002 Jan;97(1):204-6. doi: 10.1111/j.1572-0241.2002.05404.x.
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Infectious disease complications of GI endoscopy: part II, exogenous infections.胃肠内镜检查的感染性疾病并发症:第二部分,外源性感染。
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[Risk of contamination by hepatitis C of endoscopes utilized in gastroenterology hospital service].
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