Conlan A A, Payne W S, Woolner L B, Sanderson D R
J Thorac Cardiovasc Surg. 1978 Sep;76(3):369-77.
A review was made of the presentation, treatment, and follow-up of 20 patients with adenoid cystic carcinoma and 12 patients with mucoepidermoid carcinoma of the bronchus who were seen at the Mayo Clinic during the 50 year period 1927 through 1977. Three forms of therapy were employed: complete surgical resection, radiation therapy alone, and radiation therapy after endoscopic removal of tumor tissue. Superior results were obtained in the group with adenoid cystic carcinoma, when complete resection was possible. Significant survival and palliation of sepsis was achieved with subtotal resection. The mucoepidermoid carcinomas in this series were classified on the basis of histologic differentiation. Mucoepidermoid carcinoma of Grade 1 was managed by conservative pulmonary resection. Mucoepidermoid carcinoma of Grades 2 and 3 showed a greater propensity for malignancy. Widespread dissemination caused death with unresectable high-grade mucoepidermoid carcinomas of Grades 2 and 3.
回顾了1927年至1977年这50年间在梅奥诊所就诊的20例支气管腺样囊性癌患者和12例支气管黏液表皮样癌患者的临床表现、治疗及随访情况。采用了三种治疗方式：完整手术切除、单纯放射治疗以及在内镜下切除肿瘤组织后进行放射治疗。对于腺样囊性癌患者，如果能够进行完整切除，则效果更佳。次全切除可显著延长生存期并缓解脓毒症。本系列中的黏液表皮样癌根据组织学分化程度进行分类。1级黏液表皮样癌采用保守性肺切除术治疗。2级和3级黏液表皮样癌的恶性倾向更大。2级和3级高分级黏液表皮样癌因广泛播散而无法切除，导致患者死亡。
