Department of Chemistry, University of Prince Edward Island, 550 University Avenue, Charlottetown, PE, C1A 4P3, Canada.
Biomacromolecules. 2010 Dec 13;11(12):3673-9. doi: 10.1021/bm101140d. Epub 2010 Oct 29.
The synthesis of a family of polymer stars with arms of varied tacticities is discussed. The effect of polymer tacticity on the physical properties of these polymer stars is presented. Dipentaerythritol cores support six poly(lactic acid) (PLA) arms. Lewis acidic tin and aluminum catalysts control the polymerization to afford polymer stars of variable tacticity. The analysis of these polymers by NMR spectroscopy, thermogravimetric analysis, powder X-ray diffraction, and differential scanning calorimetry reveals the effects of tacticity control on the physical properties of the polymer stars. Preliminary decomposition studies suggest that the biodegradation profile of a polymer star may also be tuned by stereochemical control. This is the first systematic altering of tacticity in PLA polymer stars, showing that polymer tacticity can have a great impact on star properties.
本文讨论了具有不同立构规整性臂的聚合物星的合成。介绍了聚合物立构规整性对这些聚合物星物理性能的影响。季戊四醇核支撑六个聚（乳酸）（PLA）臂。路易斯酸锡和铝催化剂控制聚合，得到具有不同立构规整性的聚合物星。通过 NMR 光谱、热重分析、粉末 X 射线衍射和差示扫描量热法对这些聚合物进行分析，揭示了立构规整性控制对聚合物星物理性能的影响。初步的分解研究表明，聚合物星的生物降解特性也可以通过立体化学控制进行调节。这是首次在 PLA 聚合物星中系统地改变立构规整性，表明聚合物的立构规整性对星形聚合物的性能有很大的影响。
