Coppi Gioacchino, Rametta Francesco, Aiello Stefano, Saitta Giuseppe, Gennai Stefano, Silingardi Roberto
Department of Vascular Surgery, University of Modena, Modena, Italy.
Ann Vasc Surg. 2010 Nov;24(8):1053-9. doi: 10.1016/j.avsg.2010.03.031.
To investigate long-term outcomes for inflammatory abdominal aortic aneurysms (IAAA) after endovascular treatment (EVAR).
Between May 1997 and January 2009, 9 male patients (Mean 67 years, range 54-75 years) with IAAA were treated with EVAR using commercially available endografts. Results were assessed using contrast-enhanced computed tomography (CT) at 3 months, 12 months, and biannually thereafter. Echo-color duplex scanning was also recommended at 3, 6, and 12 months after discharge, and annually thereafter. Primary endpoints were aneurysm-related mortality, aneurysm sac evolution, perianeurysmal fibrosis (PAF) thickness, and hydronephrosis progression.
No aneurysm-related deaths were observed during the long-term follow-up of eight patients (one patient death unknown). Maximum aneurysm sac diameter progressively reduced in eight patients (89%) and remained unchanged in one (11%). The absolute mean reduction of the aneurysm size was 26.2%. PAF regressed in two patients (22%), reduced in five (56%), and remained unchanged in two (22%). The absolute median reduction of the PAF thickness was 55.1%. No endoleak was observed during the follow-up period. Hydronephrosis persisted in all three patients who were preoperatively diagnosed with this pathology. Survival rates were 89%, 66.7%, and 66.7% at 12, 36, and 60 months, respectively.
This series suggests that EVAR for IAAA into the long-term is associated with a positive trend for both PAF and aneurysm diameter reduction. EVAR does not seem to offer any benefits for hydronephrosis, but seems to effectively exclude the aneurysm sac in anatomically suitable patients.
探讨腔内治疗(EVAR)炎性腹主动脉瘤(IAAA)的长期疗效。
1997年5月至2009年1月,9例男性IAAA患者(平均67岁,范围54 - 75岁)接受了使用市售腔内移植物的EVAR治疗。在术后3个月、12个月及之后每半年使用增强CT评估结果。出院后3个月、6个月和12个月以及之后每年也建议进行超声彩色双功扫描。主要终点为动脉瘤相关死亡率、瘤囊演变、瘤周纤维化(PAF)厚度和肾积水进展。
8例患者长期随访期间未观察到动脉瘤相关死亡(1例患者死亡情况不明)。8例患者(89%)的最大瘤囊直径逐渐缩小,1例(11%)保持不变。动脉瘤大小的绝对平均缩小率为26.2%。2例患者(22%)的PAF消退,5例(56%)减轻,2例(22%)保持不变。PAF厚度的绝对中位数减少率为55.1%。随访期间未观察到内漏。术前诊断为肾积水的3例患者肾积水均持续存在。12个月、36个月和60个月时的生存率分别为89%、66.7%和66.7%。
本系列研究表明,IAAA的EVAR长期来看与PAF和动脉瘤直径缩小的积极趋势相关。EVAR似乎对肾积水无任何益处,但对于解剖结构合适的患者似乎能有效隔绝瘤囊。