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在阿尔茨海默病和多发性梗死性痴呆中,杏仁核和海马体均出现严重萎缩。

Severe atrophy of amygdala and hippocampus in both Alzheimer's disease and multi-infarct dementia.

作者信息

Matsuzawa T, Hishinuma T, Matsui H, Meguro K, Ueda M, Kinomura S, Yamada K

机构信息

Department of Radiology and Nuclear Medicine, Tohoku University, Sendai, Japan.

出版信息

Sci Rep Res Inst Tohoku Univ Med. 1990 Dec;37(1-4):23-5.

PMID:2103656
Abstract

Alzheimer's disease and multi-infarct dementia are the two main diseases entirely different from each other producing almost the same abnormalities as dementia syndrome. With magnetic resonance imaging, severe atrophy of amygdala and hippocampus in both Alzheimer's disease and multi-infarct dementia was observed. There was no essential difference on the atrophic findings between Alzheimer's disease and multi-infarct dementia. This result therefore suggest that the quantitative measurement of amygdaloid and hippocampal atrophy predicts dementia.

摘要

阿尔茨海默病和多发性梗死性痴呆是两种完全不同的主要疾病,它们产生与痴呆综合征几乎相同的异常情况。通过磁共振成像观察到,阿尔茨海默病和多发性梗死性痴呆患者的杏仁核和海马体均出现严重萎缩。阿尔茨海默病和多发性梗死性痴呆在萎缩表现上没有本质区别。因此,这一结果表明,杏仁核和海马体萎缩的定量测量可预测痴呆。

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Severe atrophy of amygdala and hippocampus in both Alzheimer's disease and multi-infarct dementia.在阿尔茨海默病和多发性梗死性痴呆中,杏仁核和海马体均出现严重萎缩。
Sci Rep Res Inst Tohoku Univ Med. 1990 Dec;37(1-4):23-5.
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Use of hippocampal and amygdalar volumes on magnetic resonance imaging to predict dementia in cognitively intact elderly people.利用磁共振成像测量海马体和杏仁核体积来预测认知功能正常老年人的痴呆症。
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A comparative study of five mouse models of Alzheimer's disease: cell cycle events reveal new insights into neurons at risk for death.五种阿尔茨海默病小鼠模型的比较研究:细胞周期事件揭示了对有死亡风险神经元的新见解。
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