Walker E A, Roy-Byrne P P, Katon W J, Li L, Amos D, Jiranek G
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle 98195.
Am J Psychiatry. 1990 Dec;147(12):1656-61. doi: 10.1176/ajp.147.12.1656.
Structured psychiatric interviews and psychological self-report measures were administered to 28 patients with irritable bowel syndrome and 19 patients with inflammatory bowel disease. Significantly more of the patients with irritable bowel syndrome had lifetime diagnoses of major depression, somatization disorder, generalized anxiety disorder, panic disorder, and phobic disorder. They had significantly more medically unexplained somatic symptoms, and most had suffered from psychiatric disorders, particularly anxiety disorders, before the onset of their irritable bowel symptoms.
对28名肠易激综合征患者和19名炎症性肠病患者进行了结构化精神科访谈和心理自评量表测试。肠易激综合征患者中,终生被诊断为重度抑郁症、躯体化障碍、广泛性焦虑症、惊恐障碍和恐惧症的人数明显更多。他们有明显更多的医学上无法解释的躯体症状,并且大多数人在出现肠易激症状之前就患有精神疾病,尤其是焦虑症。