Bannaga Ayman S, Selinger Christian P
Department of Gastroenterology, Doncaster Royal Infirmary, Doncaster, UK.
Department of Gastroenterology, St James University Hospital, Leeds, UK.
Clin Exp Gastroenterol. 2015 Mar 23;8:111-7. doi: 10.2147/CEG.S57982. eCollection 2015.
Inflammatory bowel disease (IBD) causes severe physical symptoms and is also associated with psychological comorbidities. Abnormal anxiety levels are found in up to 40% of patients with IBD. Anxiety symptoms are often related to flares of IBD but may persist in times of remission. Detection of anxiety disorder (AD) in patients with IBD can be challenging. Patients with anxiety may also exhibit symptoms in keeping with functional gastrointestinal disorders (FGID). Evidence for the effectiveness of pharmacological and psychological therapies for anxiety stems from patients without IBD. Studies in patients with IBD have either been small or shown negative results. In light of this, a combined approach involving IBD physicians to improve disease control and psychologists or psychiatrists to treat anxiety is advised. This review examines the evidence of anxiety issues in IBD with a focus on extent of the problem, risk factors for anxiety, and the effectiveness of interventions.
炎症性肠病(IBD)会引发严重的身体症状,还与心理共病有关。高达40%的IBD患者存在异常焦虑水平。焦虑症状常与IBD发作相关,但在缓解期也可能持续存在。在IBD患者中检测焦虑症(AD)可能具有挑战性。焦虑患者也可能表现出符合功能性胃肠疾病(FGID)的症状。针对焦虑的药物和心理治疗有效性的证据来源于非IBD患者。对IBD患者的研究要么规模较小,要么显示出阴性结果。鉴于此,建议采用一种联合方法,由IBD医生改善疾病控制,由心理学家或精神科医生治疗焦虑。本综述审视了IBD中焦虑问题的证据,重点关注问题的严重程度、焦虑的风险因素以及干预措施的有效性。