Ahmed I, Robinson C M, Patton J T, Cook R E
Fife Health Trust, Queen Margaret Hospital, Dunfermline KY12 0SU, UK.
J Bone Joint Surg Br. 2010 Nov;92(11):1592-5. doi: 10.1302/0301-620X.92B11.24715.
We present two cases of metastatic lung cancer which occurred at the site of a previously united tibial fracture. Both patients were treated with a locked intramedullary nail. The patients presented with metastases at the site of their initial fracture approximately 16 and 13 months after injury respectively. We discuss this unusual presentation and review the relevant literature. We are unaware of any previous reports of a metastatic tumour occurring at the site of an orthopaedic implant used to stabilise a non-pathological fracture. These cases demonstrate the similar clinical presentation of infection and malignancy: a diagnosis which should always be considered in such patients.
我们报告两例转移性肺癌病例，其发生于既往愈合的胫骨骨折部位。两名患者均接受了带锁髓内钉治疗。患者分别在受伤后约16个月和13个月时，在其初始骨折部位出现转移。我们讨论了这种不寻常的表现，并回顾了相关文献。我们未发现之前有任何关于转移性肿瘤发生于用于稳定非病理性骨折的骨科植入物部位的报道。这些病例表明感染和恶性肿瘤有相似的临床表现：对此类患者应始终考虑这种诊断。
