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治疗:TNF 阻滞剂对乙肝病毒感染者安全吗?

Therapy: Are TNF blockers safe for patients with hepatitis B virus infection?

机构信息

Institut d'Investigacions Biomèdiques August Pi i Sunyer, Department of Autoimmune Diseases, Laboratory of Autoimmune Diseases Josep Font, Villarroel 170, Barcelona 08036, Spain.

出版信息

Nat Rev Rheumatol. 2010 Nov;6(11):618-20. doi: 10.1038/nrrheum.2010.156.

Abstract

Immunosuppression has been associated with viral reactivation in patients with chronic viral infections. a prospective study has concluded that it is safe to use anti-tumor-necrosis-factor agents in patients with chronic hepatitis B virus infection receiving antiviral prophylaxis. Is there sufficient evidence to back up this conclusion?

摘要

免疫抑制与慢性病毒感染患者的病毒再激活有关。一项前瞻性研究得出结论,在接受抗病毒预防治疗的慢性乙型肝炎病毒感染患者中使用抗肿瘤坏死因子药物是安全的。这一结论有足够的证据支持吗?

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