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[安达卢西亚一家医院溃疡性结肠炎的回顾性研究]

[Retrospective study of ulcerative colitis at an Andalusian hospital].

作者信息

Nogueras F, Martínez Salmerón J F, Rodrigo Moreno M, García Montero M, Lacarcel E, Pleguezuelo J

机构信息

Servicio de Aparato Digestivo, Ciudad Sanitaria Virgen de las Nieves, Granada.

出版信息

An Med Interna. 1990 Apr;7(4):182-5.

PMID:2103783
Abstract

We reviewed 96 cases of ulcerative colitis diagnosed during the period between 1970 and 1988, with the intention of analysing the presentation, complications, evolution and diagnosis aspects. The most frequent presentation symptoms were mucoid and bloody diarrhea (91.3%) and abdominal pain (84%), isolated rectal bleeding being predominated in distal type. The frequency of complications were 17.14%. X-ray findings were the lack of haustration and ulcers, the rate of normal barium enema being of 27.27% (without double contrast). Rectum was not affected in 6.8%. The endoscopy showed an edematous and congestive mucosa, ulcer with normal barium enema. The most significant anatomopathological findings were the lymphoplasmocyte and polynuclear infiltration of the proper lamina and epithelial ulcer, with a lack of cripta and absence of metaplasia of Paneth's cells. In our area, we have to use colonoscopy to diagnose the disease, because the double contrast barium enema is not performed as a routine. Only a few (5) of our patients needed surgical treatment.

摘要

我们回顾了1970年至1988年期间诊断的96例溃疡性结肠炎病例,旨在分析其临床表现、并发症、病情发展及诊断方面。最常见的临床表现症状为黏液脓血便(91.3%)和腹痛(84%),远端型以单纯直肠出血为主。并发症发生率为17.14%。X线表现为结肠袋消失和溃疡形成,常规钡剂灌肠(无双重对比)正常率为27.27%。6.8%的患者直肠未受累。内镜检查显示黏膜水肿、充血,溃疡形成,钡剂灌肠正常。最显著的解剖病理学发现为固有层淋巴细胞和浆细胞浸润以及多核细胞浸润,上皮溃疡形成,隐窝缺失,潘氏细胞无化生。在我们地区,由于双重对比钡剂灌肠不作为常规检查,我们必须使用结肠镜来诊断该病。我们只有少数(5例)患者需要手术治疗。

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