The University of Queensland, National Research Centre for Environmental Toxicology-EnTox, Coopers Plains, QLD, Australia.
Chem Res Toxicol. 2010 Nov 15;23(11):1647-9. doi: 10.1021/tx100333r. Epub 2010 Nov 1.
X-ray absorption spectroscopy of frozen intact tissues shows that in rats exposed to a range of treatments involving cadmium, alone or in combination with other metal ions, the coordination environment of cadmium is consistent in both the liver and kidney. Comparison of the spectra from the rat tissues to biologically relevant model compounds indicates that the vast majority of the cadmium is bound to metallothionein in these tissues.
X 射线吸收光谱法研究冰冻完整组织表明,在接触一系列涉及镉的处理方法的大鼠中,无论是单独接触还是与其他金属离子共同接触,镉在肝和肾中的配位环境都是一致的。将大鼠组织的光谱与生物相关的模型化合物进行比较表明,这些组织中绝大多数的镉与金属硫蛋白结合。