Department of Pathology and Laboratory Medicine, Shaheed Beheshti University of Medical Sciences, Tehran, Iran.
Arch Iran Med. 2010 Nov;13(6):552-5.
The cerebellopontine angle is an extremely rare site for the growth of a choroid plexus papilloma. The clinicoradiological diagnosis of this tumor in the cerebellopontine angle is difficult because of its rarity in addition to a nonspecific clinical presentation and radiological features. Herein, we report the case of a 49-year-old woman with complaints of headache and features of raised intracranial pressure, whose computerized tomography (CT) and magnetic resonance imaging (MRI) were suggestive of acoustic neuroma or meningioma with hydrocephalus. Histology revealed multiple arborizing papillae with a central fibrovascular core, lined by cubo-columnar cells. The cells showed diffuse immunoreactivity for pancytokeratin, S100 protein, synaptophysin, and vimentin, as well as focal expression of glial fibrillary acidic protein, epithelial membrane antigen, and cytokeratin 7. English medical literature is also reviewed.
桥小脑角是脉络丛乳头状瘤生长的极罕见部位。由于其罕见性以及非特异性的临床表现和影像学特征，该肿瘤在桥小脑角的临床放射学诊断较为困难。本文报告了一例 49 岁女性，因头痛和颅内压升高的特征就诊，其计算机断层扫描（CT）和磁共振成像（MRI）提示为听神经瘤或脑膜瘤伴脑积水。组织学显示多个具有中央纤维血管核心的树枝状乳头，由立方形柱状细胞排列。这些细胞弥漫表达细胞角蛋白、S100 蛋白、突触素和波形蛋白，以及神经胶质纤维酸性蛋白、上皮膜抗原和细胞角蛋白 7 的局灶性表达。还回顾了英文医学文献。
