NeuroOncology Program, H. Lee Moffitt Cancer Center & Research Institute, Florida, USA.
J Neurosurg Spine. 2010 Nov;13(5):622-9. doi: 10.3171/2010.5.SPINE09848.
Posterior instrumentation is the preferred method of fixation in the unstable cervicothoracic junction (CTJ). Several posterior rod constructs of different diameters and configurations are available for instrumentation across the CTJ. The objective of this study was to compare the biomechanical stability of various posterior instrumentation techniques that cross the CTJ after a 2-column injury through the complete removal of the posterior elements at C-7.
Eight fresh-frozen human cadaveric spines (C3-T4) were used. After the intact spine analysis, each specimen was destabilized (C-7 laminectomy and bilateral facetectomies) and reconstructed as follows: Group 1, C5-T2 posterior instrumentation with a 3.5-mm rod; Group 2, C5-T2 posterior instrumentation with a transitional rod (3.5-5.5 mm); and Group 3, C5-T2 posterior instrumentation with a side-to-side rod connector (3.5-5.5 mm). All reconstructed groups were tested with posterior instrumentation using the Cervifix system (Synthes, Inc.). The authors hypothesized that Group 2 would be the most stable.
Following laminectomy, facetectomy, and the application of instrumentation, there was a decrease in the range of motion in all treatment groups compared with the intact spine. This trend was observed in all 3 planes of motion, but was only significant on right/left lateral bending and flexion (for the transitional rod only). Although the instrumented spines were stiffer than the intact spine in right/left axial rotation, flexion, and extension, these differences did not reach statistical significance. Based on observations during testing, it was evident that in the implanted spines, most of the motion that did occur was localized at the segments adjacent to the instrumented levels.
Based on the results of this investigation, the biomechanical stability of the transitional rod, side-to-side connector ("wedding band"), and 3.5-mm rods appears to be similar.
在不稳定的颈胸交界处(CTJ),后路器械固定是首选方法。有几种不同直径和构型的后路杆构建可供选择,用于在 CTJ 处进行器械固定。本研究的目的是比较通过完全切除 C-7 后的部元素,在 2 柱损伤后,穿过 CTJ 的各种后路器械固定技术的生物力学稳定性。
使用 8 个新鲜冷冻的人体脊柱(C3-T4)标本。在完整脊柱分析后,每个标本均不稳定(C-7 椎板切除术和双侧关节突切除术)并重建如下:第 1 组,C5-T2 后路器械固定,使用 3.5mm 杆;第 2 组,C5-T2 后路器械固定,使用过渡杆(3.5-5.5mm);第 3 组,C5-T2 后路器械固定,使用侧对侧杆连接器(3.5-5.5mm)。所有重建组均使用 Cervifix 系统(Synthes,Inc.)进行后路器械固定测试。作者假设第 2 组将是最稳定的。
在椎板切除、关节切除和器械应用后,与完整脊柱相比,所有治疗组的活动范围均减小。这种趋势在所有 3 个运动平面上都观察到,但仅在右侧/左侧侧屈和前屈(仅过渡杆)时具有统计学意义。虽然植入脊柱在右侧/左侧轴向旋转、前屈和伸展时比完整脊柱更僵硬,但这些差异没有达到统计学意义。根据测试期间的观察,很明显,在植入的脊柱中,大多数发生的运动都局限在与器械固定水平相邻的节段。
根据本研究的结果,过渡杆、侧对侧连接器(“结婚戒指”)和 3.5mm 杆的生物力学稳定性似乎相似。