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在家中使用口服皮质类固醇预防哮喘患者的急诊科就诊和住院:我们是否遵循了国家指南?

Preventing emergency department visits and hospitalizations for asthma by use of oral corticosteroids at home: are we adhering to national guidelines?

作者信息

Self Timothy H, Chrisman Cary R, Jacobs Anna R, Vo Ngan H, Winton John C

机构信息

College of Pharmacy, University of Tennessee Health Science Center and Methodist University Hospital, Memphis, TN 38163, USA.

出版信息

J Asthma. 2010 Dec;47(10):1123-7. doi: 10.3109/02770903.2010.514641. Epub 2010 Nov 1.

Abstract

BACKGROUND

Oral corticosteroids (OCS) in the home management of asthma exacerbations have been recommended in the NIH/NHLBI guidelines since 1991. As a routine component of written action plans, OCS treatment at home is associated with reduced emergency department (ED) visits and hospitalizations as well as decreased mortality.

METHODS

A literature search of English language journals from 1991 to 2009 was performed using several databases, including PubMed, EMBASE, and SCOPUS. We assessed studies that evaluated adherence to national guidelines for home management of asthma exacerbations.

RESULTS

Our review of the literature found that several studies reveal that a small percentage (<3-26%) of patients are receiving OCS at home to manage asthma exacerbations prior to an ED visit. Additional studies were found showing very low use of written action plans, strongly suggesting lack of OCS for home management of asthma exacerbations.

CONCLUSIONS

Despite evidence of reduced ED visits and hospitalizations and the recommendations of national and international guidelines, the home use of OCS in managing asthma exacerbations remains unacceptably low. New strategies are needed to ensure home use of OCS as part of written action plans to prevent ED visits and hospitalizations for asthma exacerbations.

摘要

背景

自1991年以来,美国国立卫生研究院/美国国立心肺血液研究所(NIH/NHLBI)指南就推荐在家中使用口服皮质类固醇(OCS)治疗哮喘急性发作。作为书面行动计划的常规组成部分,在家中进行OCS治疗可减少急诊就诊和住院次数,并降低死亡率。

方法

使用包括PubMed、EMBASE和SCOPUS在内的多个数据库,对1991年至2009年的英文期刊进行文献检索。我们评估了那些评估哮喘急性发作家庭管理指南依从性的研究。

结果

我们对文献的综述发现,多项研究表明,在急诊就诊前,只有一小部分(<3-26%)患者在家中使用OCS来治疗哮喘急性发作。还发现其他研究显示书面行动计划的使用率极低,这强烈表明在家中管理哮喘急性发作时缺乏OCS。

结论

尽管有证据表明急诊就诊和住院次数减少,且有国家和国际指南的推荐,但在家中使用OCS治疗哮喘急性发作的情况仍然低得令人无法接受。需要新的策略来确保将在家中使用OCS作为书面行动计划的一部分,以预防因哮喘急性发作而导致的急诊就诊和住院。

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