Wang Hong, Zhang Weiyuan, Liu Tao
Beijing Anzhen Hospital of Capital Medical University, Beijing, China.
J Obstet Gynaecol Res. 2011 Jan;37(1):64-70. doi: 10.1111/j.1447-0756.2010.01321.x. Epub 2010 Oct 11.
To determine maternal and fetal outcomes in patients with Eisenmenger's syndrome (ES) with the therapeutic strategy.
MATERIAL & METHODS: The case histories and therapeutic procedures of 13 pregnant women with ES had been reviewed.
One case spontaneously aborted before 28 weeks due to intrauterine death, four were taken to cesarean section before 28 weeks and eight (61.5%) survived beyond 28 weeks' gestation before cesarean section. One mother died (92.3% survival), while infant loss was 38.5%. No pregnancy continued to term but eight babies delivered after 28 weeks were born alive, six of the children have normal physical and mental development.
In pregnant women with ES who wish to continue pregnancy, treatment should include: prolonged bedrest, continuous oxygen inhalation, diuretic administration with close hemodynamic monitoring, anticoagulants should be avoided and exact time point selection of cesarean section.
确定采用该治疗策略的艾森曼格综合征（ES）患者的母婴结局。
回顾了13例ES孕妇的病史和治疗过程。
1例因宫内死亡在28周前自然流产，4例在28周前接受剖宫产，8例（61.5%）在剖宫产前行妊娠超过28周。1例母亲死亡（生存率92.3%），婴儿丢失率为38.5%。无妊娠至足月，但28周后分娩的8例婴儿存活，其中6名儿童身心发育正常。
对于希望继续妊娠的ES孕妇，治疗应包括：延长卧床休息、持续吸氧、给予利尿剂并密切监测血流动力学，应避免使用抗凝剂以及准确选择剖宫产时间点。
