Department of Ophthalmology, Flinders Medical Centre, Bedford Park, South Australia, Australia.
Emerg Med Australas. 2010 Oct;22(5):477-9. doi: 10.1111/j.1742-6723.2010.01338.x.
We present a case of a 63-year-old woman who presented to an ED with bifrontal headache, nausea and vomiting and reduced visual acuity. Examination revealed bilateral elevated intraocular pressures, corneal haze, shallow anterior chambers and poorly reactive, mid-dilated pupils. Diagnosis was made of simultaneous bilateral acute angle closure glaucoma. A complete drug history revealed that she had been using an over-the-counter cold and flu remedy whose active ingredients included atropa belladonna, an herb with anticholinergic properties. It is likely that drug-induced dilatation of the individual's pupils precipitated this angle closure emergency. In the report we discuss the risk factors for angle closure glaucoma, and review the local and systemic drugs known to trigger this sight-threatening emergency.
我们报告了 1 例 63 岁女性病例,她因双侧额部头痛、恶心呕吐和视力下降而到急诊科就诊。检查发现双侧眼内压升高,角膜混浊,前房浅,瞳孔中度散大且反应迟钝。诊断为双侧急性闭角型青光眼。完整的药物史显示,她一直在使用一种非处方感冒和流感药物,其有效成分包括颠茄,一种具有抗胆碱能特性的草药。很可能是药物引起的个体瞳孔扩张引发了这种闭角性紧急情况。在报告中,我们讨论了闭角型青光眼的危险因素,并回顾了已知可引发这种威胁视力的紧急情况的局部和全身药物。