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[肠结核作为炎症性肠病的鉴别诊断]

[Intestinal tuberculosis as a differential diagnosis of inflammatory bowel disease].

作者信息

Lødrup Anders, Eiholm Susanne, Meyer Christian, Bremholm Lasse

机构信息

Køge Sygehus, Medicinsk Afdeling, Denmark.

出版信息

Ugeskr Laeger. 2010 Oct 18;172(42):2902-3.

Abstract

Intestinal tuberculosis (ITB) is a rare differential diagnosis of inflammatory bowel disease (IBD) in Denmark. In the presented case, a 44-year-old native Danish man was examined for IBD symptoms. Colonoscopy and microscopy of colonic biopsies suggested IBD. The patient was started on steroid therapy, but without effect so tumour necrosis factor alpha therapy was planned. Routine interferon-gamma release assay was normal, but chest X-ray revealed an apical infiltration. New tests on the colonic biopsies using polymerase chain reaction were positive for Mycobacterium tuberculosis and the patient was treated for ITB and pulmonary tuberculosis.

摘要

肠结核(ITB)在丹麦是炎症性肠病(IBD)一种罕见的鉴别诊断疾病。在本病例中,一名44岁的丹麦本土男子因IBD症状接受检查。结肠镜检查及结肠活检组织显微镜检查提示为IBD。该患者开始接受类固醇治疗,但无效,因此计划采用肿瘤坏死因子α治疗。常规干扰素-γ释放试验结果正常,但胸部X线检查显示肺尖浸润。对结肠活检组织进行的聚合酶链反应新检测结果显示结核分枝杆菌呈阳性,该患者接受了肠结核和肺结核治疗。

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