Federspiel Birgitte Hartnack, Hansen Carsten Palnaes, Vainer Ben, Hasselby Jane Preuss, Bardram Linda, Knigge Ulrich
Patologiafdelingen, Rigshospitalet, 2100 København Ø, Denmark.
Ugeskr Laeger. 2010 Oct 25;172(43):2946-50.
Gastro-entero-pancreatic neuroendocrine tumours (GEP NETs) are unusual. Their incidence, the different tumour types and growth patterns are described. The tumours should be classified according to the WHO 2000 classification and the Tumour Node Metastasis classification according to guidelines from the European Neuroendocrine Tumour Society. Important parameters are localization, size, hormonal secretion, mitotic index, and proliferation index (Ki-67) of the primary tumour. Patients with GEP NET should be referred to as few centres as possible in order to obtain the highest experience and the greatest understanding of these tumours thereby achieving the capacity to offer patients the best possible treatment and to create optimal conditions for research.
胃肠胰神经内分泌肿瘤（GEP NETs）较为罕见。本文描述了其发病率、不同的肿瘤类型及生长模式。这些肿瘤应根据世界卫生组织2000年分类标准以及欧洲神经内分泌肿瘤学会指南中的肿瘤淋巴结转移分类进行归类。重要参数包括原发肿瘤的定位、大小、激素分泌、有丝分裂指数以及增殖指数（Ki-67）。GEP NET患者应尽可能转诊至少数几个中心，以便获取关于这些肿瘤的最高水平经验和最深入理解，从而有能力为患者提供最佳治疗，并为研究创造最优条件。
