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与每日四次每次1克相比,十二指肠溃疡患者每日睡前服用2克硫糖铝可实现愈合。

Duodenal ulcer healing on 2 g of sucralfate daily at bedtime compared to 1 g four times daily.

作者信息

Bendtsen F, Ebbehøj N, Fallingborg J, Abildgaard K, Mortensen P B, Matzen P, Krag E, Kromann-Andersen H

机构信息

Department of Medical Gastroenterology, Hvidovre Hospital, Copenhagen, Denmark.

出版信息

Aliment Pharmacol Ther. 1990 Feb;4(1):97-9. doi: 10.1111/j.1365-2036.1990.tb00453.x.

Abstract

Seventy-seven patients with endoscopically verified duodenal ulcers were randomized to treatment with either 2 g sucralfate daily at bedtime or 1 g sucralfate q.d.s. in a controlled double-blind comparative study. After a 4-week treatment period, the healing rate was 68% for the former and 69% for the latter treatment.

摘要

在一项对照双盲比较研究中,77例经内镜证实为十二指肠溃疡的患者被随机分为两组,一组在睡前每日服用2克硫糖铝,另一组每日四次、每次服用1克硫糖铝。经过4周的治疗期后,前一组的愈合率为68%,后一组为69%。

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