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阴道内给予曲普瑞林处理断奶母猪的排卵和发情同步受给药时间和卵泡大小的影响。

Synchronization of ovulation and fertility in weaned sows treated with intravaginal triptorelin is influenced by timing of administration and follicle size.

机构信息

Department of Animal Science, University of Illinois, 360 Animal Science Lab, 1207 West Gregory Drive, MC-630 Urbana, Illinois, USA.

出版信息

Theriogenology. 2011 Jan 15;75(2):308-19. doi: 10.1016/j.theriogenology.2010.09.001. Epub 2010 Oct 30.

Abstract

A 100 μg dose of triptorelin was tested for synchronizing ovulation in sows. In Experiment 1, conducted in April through June, sows (n = 125) were assigned to Control (untreated), TG-96 (Triptorelin Gel (TG) given intravaginally at 96 h post-weaning), or TG-E (given intravaginally at estrus). To optimize AI timing, sows were inseminated at 2 and 26 h after estrus for Control and TG-E and at 8 and 32 h following TG-96. Ovulation by 48 h post-treatment tended to be affected by treatment (P = 0.08) and more (P < 0.05) TG-96 sows ovulated (57.9%) compared to Controls (34.2%), but TG-E (45.1%) did not differ (P > 0.10). Duration of estrus was reduced (P < 0.005) in TG-96 (51 h) and TG-E (58 h) compared to Controls (65 h). There was no treatment effect on farrowing rate (71%) or total born (10.4). Average follicle size <6.5 mm at 96 h after weaning was associated with reduced (P < 0.01) estrus, ovulation and farrowing rate. Experiment 2 was conducted in August through September using 503 weaned sows. The TG-96 treatment reduced duration of estrus (P = 0.03), but treatment did not affect estrus expression, farrowing rate or total pigs born. In conclusion, use of a 100 μg dose of triptorelin intravaginally at 96 h or at estrus advanced ovulation and when used with timed insemination, resulted in similar farrowing rates and litter sizes comparable to sows mated based on estrus. However, ovulation induction and timed AI success may benefit from an approach that ensures sows have adequate follicle development at time of treatment.

摘要

100μg 剂量的曲普瑞林被测试用于同步母猪排卵。在 4 月至 6 月进行的实验 1 中,将 125 头母猪分配到对照组(未处理)、TG-96 组(断奶后 96 小时经阴道给予曲普瑞林凝胶(TG))或 TG-E 组(发情时经阴道给予)。为了优化人工授精时间,对照组和 TG-E 组在发情后 2 小时和 26 小时进行授精,TG-96 组在发情后 8 小时和 32 小时进行授精。处理后 48 小时排卵的情况倾向于受到处理的影响(P=0.08),并且与对照组(34.2%)相比,更多的 TG-96 组母猪(57.9%)排卵(P<0.05),但 TG-E 组(45.1%)没有差异(P>0.10)。发情持续时间在 TG-96 组(51 小时)和 TG-E 组(58 小时)中缩短(P<0.005),与对照组(65 小时)相比。产仔率(71%)或总产仔数(10.4)不受处理影响。断奶后 96 小时平均卵泡大小<6.5mm 与发情、排卵和产仔率降低有关(P<0.01)。实验 2 于 8 月至 9 月使用 503 头断奶母猪进行。TG-96 处理缩短了发情持续时间(P=0.03),但处理不影响发情表现、产仔率或总产仔数。总之,阴道内使用 100μg 剂量的曲普瑞林,在断奶后 96 小时或发情时使用,可提前排卵,与定时人工授精相结合,可获得与根据发情配种的母猪相似的产仔率和产仔数。然而,排卵诱导和定时人工授精的成功可能受益于一种方法,该方法可确保在治疗时母猪有足够的卵泡发育。

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