Miller J D, Sakalas R, Ward J D, Young H F, Adams W E, Vries J K, Becker D P
Neurosurgery. 1977 Sep-Oct;1(2):114-7. doi: 10.1227/00006123-197709000-00005.
A study was made in 10 patients with brain tumors of the effect of methylprednisolone sodium succinate (Solu-Medrol) on clinical neurological status, intracranial pressure, and periventricular elastance. Significant clinical improvement and reduction in periventricular elastance both ocurred within 24 hours of starting treatment, whereas intracranaial pressure was not significantly reduced until the 2nd day of therapy.
对10例脑肿瘤患者进行了一项研究,观察琥珀酸甲泼尼龙(甲强龙)对临床神经状态、颅内压和脑室周围弹性的影响。在开始治疗后的24小时内,临床症状显著改善,脑室周围弹性降低,而颅内压直到治疗第2天才显著降低。