Fishell Alicja
Reproductive Life Stages Program, Women's College Hospital, Toronto, Canada.
J Popul Ther Clin Pharmacol. 2010 Fall;17(3):e363-9. Epub 2010 Oct 26.
The risk of depression in women is greatest during the child-bearing years. Considering that about 50% of pregnancies are unplanned, women may become pregnant while on antidepressants, may have their depression or anxiety relapse during pregnancy or postpartum, or may be unwell and untreated before and during pregnancy and the postpartum period. The impact of the symptoms of depression and anxiety can cause risk to the mother and also have a negative effect on child development. This presentation is intended to assist in understanding the impact of untreated maternal depression and anxiety on fetus, neonate, child and mother; to review the effects of fetal exposure to psychotropic medications (antidepressants); and to summarize general management of perinatal mood/anxiety disorders.
女性在生育年龄段患抑郁症的风险最高。鉴于约50%的怀孕是意外怀孕，女性可能在服用抗抑郁药期间怀孕，可能在孕期或产后抑郁症或焦虑症复发，或者在怀孕前、孕期及产后身体不适且未得到治疗。抑郁和焦虑症状的影响会给母亲带来风险，也会对儿童发育产生负面影响。本报告旨在帮助理解未治疗的孕产妇抑郁和焦虑对胎儿、新生儿、儿童及母亲的影响；回顾胎儿接触精神药物（抗抑郁药）的影响；并总结围产期情绪/焦虑障碍的一般管理。
