Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital, Victoria, Australia.
Circ J. 2010 Nov;74(12):2507-16. doi: 10.1253/circj.cj-10-0869. Epub 2010 Oct 28.
Heart failure (HF) is a highly prevalent disease that leads to significant morbidity and mortality. There is increasing evidence that the symptoms of HF are exacerbated by its deleterious effects on lung function. HF appears to cause airway obstruction acutely and leads to impaired gas diffusing capacity and pulmonary hypertension in the longer term. It is postulated that this is the result of recurrent episodes of elevated pulmonary capillary pressure leading to pulmonary oedema and pulmonary capillary stress fracture, which produces lung fibrosis. It is likely that impaired lung function impairs the functional status of HF patients and makes them more prone to central sleep apnoea.
心力衰竭（HF）是一种高发疾病，可导致严重的发病率和死亡率。越来越多的证据表明，HF 的症状因对肺功能的有害影响而加重。HF 似乎会导致气道阻塞急性发作，并在长期内导致气体弥散能力受损和肺动脉高压。据推测，这是由于反复发生的肺毛细血管压升高导致肺水肿和肺毛细血管应力性骨折，从而产生肺纤维化的结果。很可能是受损的肺功能会损害 HF 患者的功能状态，并使他们更容易发生中枢性睡眠呼吸暂停。
