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Liver: Can pentoxifylline secure its place in liver therapeutics?

作者信息

Kendrick Stuart F W, Day Chris P

机构信息

Institute of Cellular Medicine, Newcastle University, Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.

出版信息

Nat Rev Gastroenterol Hepatol. 2010 Nov;7(11):593-4. doi: 10.1038/nrgastro.2010.150.

DOI:10.1038/nrgastro.2010.150
PMID:21042337
Abstract
摘要

相似文献

1
Liver: Can pentoxifylline secure its place in liver therapeutics?肝脏:己酮可可碱能在肝脏治疗中占据一席之地吗?
Nat Rev Gastroenterol Hepatol. 2010 Nov;7(11):593-4. doi: 10.1038/nrgastro.2010.150.
2
Pharmacological aspects of pentoxifylline with emphasis on its inhibitory actions on hepatic fibrogenesis.己酮可可碱的药理学特性,重点在于其对肝纤维化形成的抑制作用。
Gen Pharmacol. 1997 Aug;29(2):181-96. doi: 10.1016/s0306-3623(96)00314-x.
3
Pentoxifylline in the management of metabolic syndrome and chronic hepatitis C.己酮可可碱在代谢综合征和慢性丙型肝炎治疗中的应用
Med Hypotheses. 2014 Dec;83(6):832-4. doi: 10.1016/j.mehy.2014.10.020. Epub 2014 Oct 28.
4
Pentoxifylline for slow to resolve hepatopulmonary syndrome post liver transplantation: helpful or unnecessary?己酮可可碱用于肝移植后缓解缓慢的肝肺综合征:有益还是多余?
Acta Gastroenterol Belg. 2013 Mar;76(1):70-1.
5
Clinical experience with pentoxifylline.
Atherosclerosis. 1997 Jun;131 Suppl:S37-9. doi: 10.1016/s0021-9150(97)06125-x.
6
On the pharmacologic protection of the liver and intestine during ischemia.
Surgery. 1998 Feb;123(2):249-50. doi: 10.1016/s0039-6060(98)70271-5.
7
[Pentoxifylline in the treatment of disorders of the cerebral circulation].己酮可可碱治疗脑循环障碍
Zh Nevrol Psikhiatr Im S S Korsakova. 1997;97(9):62-7.
8
Vascular diseases: new results with pentoxifylline.
Angiology. 2002 Jan-Feb;53 Suppl 1:1 p following TOC.
9
Prevention of hepatorenal syndrome in patients with cirrhosis and ascites: a pilot randomized control trial between pentoxifylline and placebo.预防肝硬化和腹水患者肝肾综合征:己酮可可碱与安慰剂的随机对照试验
Eur J Gastroenterol Hepatol. 2011 Mar;23(3):210-7. doi: 10.1097/MEG.0b013e3283435d76.
10
Protective effect of pentoxifylline on contrast induced nephropathy.己酮可可碱对造影剂肾病的保护作用。
Saudi J Kidney Dis Transpl. 2008 Nov;19(6):985-6.

本文引用的文献

1
Pentoxifylline does not decrease short-term mortality but does reduce complications in patients with advanced cirrhosis.己酮可可碱并不能降低晚期肝硬化患者的短期死亡率,但确实能减少并发症。
Gastroenterology. 2010 May;138(5):1755-62. doi: 10.1053/j.gastro.2010.01.040. Epub 2010 Jan 25.
2
A randomized, double-blinded, placebo-controlled multicenter trial of etanercept in the treatment of alcoholic hepatitis.一项关于依那西普治疗酒精性肝炎的随机、双盲、安慰剂对照多中心试验。
Gastroenterology. 2008 Dec;135(6):1953-60. doi: 10.1053/j.gastro.2008.08.057. Epub 2008 Sep 13.
3
Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial.
己酮可可碱可改善严重急性酒精性肝炎患者的短期生存率:一项双盲、安慰剂对照试验。
Gastroenterology. 2000 Dec;119(6):1637-48. doi: 10.1053/gast.2000.20189.
4
Bacterial infection in the pathogenesis of variceal bleeding.
Lancet. 1999 Jan 9;353(9147):139-42. doi: 10.1016/S0140-6736(98)06020-6.
5
Acute haemodynamic responses and inhibition of tumour necrosis factor-alpha by pentoxifylline in rats with cirrhosis.己酮可可碱对肝硬化大鼠急性血流动力学反应及肿瘤坏死因子-α的抑制作用
Clin Sci (Lond). 1996 Jul;91(1):29-33. doi: 10.1042/cs0910029.
6
Review: regulation of liver regeneration by pro-inflammatory cytokines.综述:促炎细胞因子对肝脏再生的调控
J Gastroenterol Hepatol. 1996 May;11(5):466-70. doi: 10.1111/j.1440-1746.1996.tb00292.x.
7
Regulation of tumour necrosis factor production by mouse peritoneal macrophages: the role of cellular cyclic AMP.小鼠腹腔巨噬细胞对肿瘤坏死因子产生的调节:细胞环磷酸腺苷的作用。
Immunology. 1988 Aug;64(4):719-24.
8
Cellular and molecular regulation of tumor necrosis factor-alpha production by pentoxifylline.己酮可可碱对肿瘤坏死因子-α产生的细胞和分子调节
Biochem Biophys Res Commun. 1988 Sep 30;155(3):1230-6. doi: 10.1016/s0006-291x(88)81271-3.
9
Pentoxifylline increases survival in murine endotoxin shock and decreases formation of tumor necrosis factor.己酮可可碱可提高小鼠内毒素休克的存活率,并减少肿瘤坏死因子的形成。
Circ Shock. 1990 Jun;31(2):171-81.
10
Increased plasma tumor necrosis factor in severe alcoholic hepatitis.重症酒精性肝炎患者血浆肿瘤坏死因子升高。
Ann Intern Med. 1990 Jun 15;112(12):917-20. doi: 10.7326/0003-4819-112-12-917.