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利用 1.06μm 超短脉冲激光系统产生类超连续谱,用于超高分辨率光学相干断层扫描。

Quasi-supercontinuum generation using 1.06 μm ultrashort-pulse laser system for ultrahigh-resolution optical-coherence tomography.

机构信息

Division of Advanced Science and Biotechnology, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.

出版信息

Opt Lett. 2010 Nov 1;35(21):3631-3. doi: 10.1364/OL.35.003631.

Abstract

We demonstrate quasi-supercontinuum (quasi-SC) generation around the 1.3 μm wavelength region using ultrahigh-speed, wavelength-tunable, femtosecond soliton pulses based on an ultrashort-pulse laser system operating at a wavelength of 1.0 μm. The wavelength tuning range was from 1.0 to 1.9 μm, and the scanning speed was up to 1.3 MHz. A Gaussian-like quasi-SC with a bandwidth of 220 nm was generated at 1220 nm. The generated quasi-SC was used in an optical-coherence tomography system. High axial resolutions of 5.1 μm in air and 3.7 μm in tissue were obtained. A maximum sensitivity of 100 dB was achieved, and ultrahigh-resolution images of a hamster cheek pouch were observed.

摘要

我们使用基于工作波长为 1.0 μm 的超短脉冲激光系统的超快、波长可调谐飞秒孤子脉冲,在 1.3 μm 波长区域演示了准超连续谱(quasi-SC)的产生。波长调谐范围从 1.0 μm 到 1.9 μm,扫描速度高达 1.3 MHz。在 1220 nm 处产生了带宽为 220nm 的高斯型准连续谱。所产生的准连续谱被用于光学相干断层扫描系统。在空气中获得了 5.1 μm 的高轴向分辨率,在组织中获得了 3.7 μm 的高轴向分辨率。实现了 100 dB 的最大灵敏度,并观察到了仓鼠颊囊的超高分辨率图像。

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