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腹腔镜根治性子宫切除术成功治疗子宫颈肉瘤样鳞状细胞癌:一例报告

Sarcomatoid squamous cell carcinoma of the uterine cervix successfully treated by laparoscopic radical hysterectomy: a case report.

作者信息

Kong Tae-Wook, Kim Jang-Hee, Chang Suk-Joon, Chang Ki-Hong, Ryu Hee-Sug, Joo Hee-Jae

机构信息

Department of Obstetrics and Gynecology, Ajou University School of Medicine, Suwon, South Korea.

出版信息

J Reprod Med. 2010 Sep-Oct;55(9-10):445-8.

Abstract

BACKGROUND

Sarcomatoid squamous cell carcinoma of the uterine cervix is a rare tumor with uncertain pathogenesis. The rarity of this neoplasm makes it difficult to diagnose and manage, and it seems to be an aggressive tumor with a short disease-free survival. To date, < 20 cases have been reported. We report the first case of sarcomatoid carcinoma successfully treated by laparoscopic radical hysterectomy.

CASE

A 26-year-old woman presented with postcoital spotting. Gynecologic examination revealed an approximately 2.5-cm-diameter mass on the posterior lip of the cervix, and biopsy revealed a sarcomatoid carcinoma. After the baseline study for cervical cancer, the patient was found to have International Federation of Obstetricians and Gynecologists stage IB1 disease. The patient underwent laparoscopic radical hysterectomy with bilateral pelvic and paraaortic lymphadenectomy. Histopathologic examination showed no evidence of parametrial tumor extension or lymph node metastasis, and no adjuvant treatment was given.

CONCLUSION

This report entails the first description of laparoscopic surgery for sarcomatoid carcinoma of the cervix. Despite short-term follow-up, it seems that early-stage disease could be successfully treated by laparoscopic radical hysterectomy.

摘要

背景

宫颈肉瘤样鳞状细胞癌是一种发病机制不明的罕见肿瘤。这种肿瘤的罕见性使其难以诊断和处理,并且它似乎是一种侵袭性肿瘤,无病生存期短。迄今为止,报道的病例<20例。我们报告首例通过腹腔镜根治性子宫切除术成功治疗的肉瘤样癌病例。

病例

一名26岁女性出现性交后点滴出血。妇科检查发现宫颈后唇有一个直径约2.5 cm的肿块,活检显示为肉瘤样癌。在进行宫颈癌的基线检查后,发现该患者为国际妇产科联盟(FIGO)IB1期疾病。患者接受了腹腔镜根治性子宫切除术及双侧盆腔和腹主动脉旁淋巴结清扫术。组织病理学检查显示未发现宫旁组织肿瘤浸润或淋巴结转移,未给予辅助治疗。

结论

本报告首次描述了腹腔镜手术治疗宫颈肉瘤样癌。尽管随访时间短,但早期疾病似乎可通过腹腔镜根治性子宫切除术成功治疗。

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