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儿童复发性细菌性脑膜炎:我们对14例病例的经验

Recurrent bacterial meningitis in children: our experience with 14 cases.

作者信息

Tuygun Nilden, Tanir Gönül, Aytekin Caner

机构信息

Dr. Sami Ulus Children's Health and Diseases Training and Research Center, Ankara, Turkey.

出版信息

Turk J Pediatr. 2010 Jul-Aug;52(4):348-53.

Abstract

Recurrent bacterial meningitis is an uncommon but life-threatening condition. The aim of this study was to evaluate the demographic, clinical, microbiological, and radiological features of recurrent bacterial meningitis in children. Fourteen patients (10 male, 4 female) treated for recurrent bacterial meningitis were reviewed. The mean age of the patients was 87 months (range: 6 months to 13 years). There were 67 episodes of meningitis documented in these 14 patients. Six patients had developmental anatomical defects, five had traumatic anatomical defects and three had primary immune deficiency diseases as predisposing conditions. We suggest that, in a case of recurrent meningitis, a pediatrician should question and examine the patient carefully in search of a possible anatomical defect or immunodeficiency. Vaccination and surgical treatment of the anatomical defects may be important.

摘要

复发性细菌性脑膜炎是一种罕见但危及生命的疾病。本研究的目的是评估儿童复发性细菌性脑膜炎的人口统计学、临床、微生物学和放射学特征。回顾了14例接受复发性细菌性脑膜炎治疗的患者(10例男性,4例女性)。患者的平均年龄为87个月(范围:6个月至13岁)。这14例患者共记录到67次脑膜炎发作。6例患者有发育性解剖缺陷,5例有创伤性解剖缺陷,3例有原发性免疫缺陷病作为易感因素。我们建议,对于复发性脑膜炎病例,儿科医生应仔细询问和检查患者,以寻找可能的解剖缺陷或免疫缺陷。解剖缺陷的疫苗接种和手术治疗可能很重要。

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