通过碘-镁交换制备 2-镁代 1,3,5-三嗪。
Preparation of 2-magnesiated 1,3,5-triazines via an iodine-magnesium exchange.
机构信息
Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, Haus F, 81377 München, Germany.
出版信息
Org Lett. 2010 Dec 3;12(23):5398-401. doi: 10.1021/ol102173z. Epub 2010 Nov 2.
Functionalized iodo- and diiodo-1,3,5-triazine derivatives readily undergo an I/Mg exchange with BuMgCl, sBuMgCl, or OctMgBr at low temperatures furnishing 2-magnesiated and 2-zincated 1,3,5-triazines (after transmetalation with ZnCl(2)). This method also offers a convenient access to dimagnesiated triazines. Furthermore, it allows the preparation of functionalized 1,3,5-triazinyl dimers and trimers, interesting for their opto-electronic properties.
功能化碘代和二碘代 1,3,5-三嗪衍生物可在低温下与 BuMgCl、sBuMgCl 或 OctMgBr 发生 I/Mg 交换，生成 2-镁代和 2-锌代 1,3,5-三嗪（经 ZnCl(2) 转金属化后）。该方法还为制备双镁代三嗪提供了便利。此外，它还可用于制备功能化的 1,3,5-三嗪基二聚体和三聚体，这些化合物具有光电性能，因此很有趣。
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