Campagnolo Paula Dal Bó, Hoffman Daniel J, Vitolo Márcia Regina
PhD Program in Health Sciences, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Brazil.
Ann Hum Biol. 2011 May;38(3):265-70. doi: 10.3109/03014460.2010.526147. Epub 2010 Nov 2.
Waist-to-height ratio (WHtR) has been recommended as a tool for predicting cardiovascular risk in children. However, there is little evidence about the accuracy of using WHtR as a predictor of disease risk in pre-school children.
To assess the accuracy of waist-to-height ratio (WHtR), waist circumference (WC) and body mass index (BMI) as well as to determine the optimal cut-off values for each of these measures in order to identify pre-school children with cardiovascular risks.
This study conducted a cross-sectional analysis of 315 children between 3-4 years of age. Multiple risk factors for cardiovascular disease (MRFCD) were defined as having two or more of the following conditions: HDL-c < 35 mg/dL, LDL-c ≥ 110 mg/dL, triglycerides ≥ 150 mg/dL and systolic and/or diastolic blood pressure ≥ 90(th) percentile.
The accuracy of WHtR in identifying cardiovascular risk in pre-school children was not significantly different compared to BMI or WC, for both sexes. The optimal cut-off measures for predicting cardiovascular risk in boys and girls, respectively, were as follows: 0.51 and 0.49 for WHtR; 0.61 and 0.69 for BMI Z-score; and 51.2 cm and 50.2 cm for WC.
The data support the use of a 0.5 cut-off value for WHtR to predict cardiovascular risk factors among pre-school children and suggest that using WHtR is comparable to both BMI and WC.
腰高比(WHtR)已被推荐作为预测儿童心血管风险的工具。然而,关于将WHtR用作学龄前儿童疾病风险预测指标的准确性,证据很少。
评估腰高比(WHtR)、腰围(WC)和体重指数(BMI)的准确性,并确定这些指标各自的最佳截断值,以识别有心血管风险的学龄前儿童。
本研究对315名3至4岁儿童进行了横断面分析。心血管疾病多重危险因素(MRFCD)定义为具有以下两种或更多情况:高密度脂蛋白胆固醇(HDL-c)<35mg/dL、低密度脂蛋白胆固醇(LDL-c)≥110mg/dL、甘油三酯≥150mg/dL以及收缩压和/或舒张压≥第90百分位数。
对于男女两性,WHtR在识别学龄前儿童心血管风险方面的准确性与BMI或WC相比无显著差异。预测男孩和女孩心血管风险的最佳截断指标分别如下:WHtR为0.51和0.49;BMI Z评分分别为0.61和0.69;WC分别为51.2cm和50.2cm。
数据支持使用0.5的WHtR截断值来预测学龄前儿童的心血管危险因素,并表明使用WHtR与BMI和WC具有可比性。