Department of Psychiatry, Graduate School of Medicine, Kyoto University, Sakyo, Kyoto, Japan.
Clin Transplant. 2011 Sep-Oct;25(5):714-20. doi: 10.1111/j.1399-0012.2010.01337.x. Epub 2010 Nov 2.
The purpose of this study was to examine psychosocial states of recipients and donors several years after living donor liver transplantation (LDLT) and to find out the pre-transplant predictors of desirable post-transplant psychosocial states. The recipients and donors of adult-to-adult LDLT at Kyoto University Hospital, Japan, from November 2001 through July 2003 were interviewed and examined by means of questionnaires about anxiety, depression, and quality of life (QOL), and the participants were evaluated by the same test batteries sent by mail three to five yr after LDLT. Twenty-seven pairs of recipients and donors, 13 recipients, and three donors participated in this study. The recipients and the donors had a decline in social QOL. The main predictor of psychosocial states of the recipients was the length of wait for LDLT, and the predictors of the donors were family or support system availability and recipients' depressive states at LDLT. The donors who were spouses of the recipients had better QOL than other donors. It might be better to perform LDLT as soon as possible once LDLT has been judged to be necessary, and the relative who is on close terms with the recipient should be selected as donor.
本研究旨在探讨活体肝移植（LDLT）数年后受者和供者的心理社会状态，并找出移植前预测理想移植后心理社会状态的因素。本研究对 2001 年 11 月至 2003 年 7 月在日本京都大学医院接受成人对成人 LDLT 的受者和供者进行了访谈和问卷调查，评估其焦虑、抑郁和生活质量（QOL），并在 LDLT 后 3 至 5 年内通过邮寄相同的测试包进行评估。共有 27 对受者和供者、13 名受者和 3 名供者参与了本研究。受者和供者的社会 QOL 下降。受者心理社会状态的主要预测因素是 LDLT 的等待时间，供者的预测因素是家庭或支持系统的可用性和 LDLT 时受者的抑郁状态。作为受者配偶的供者的 QOL 比其他供者好。一旦判断需要 LDLT，最好尽快进行 LDLT，并且应该选择与受者关系密切的亲属作为供者。
