甲氨蝶呤在银屑病关节炎患者中的应用。
Use of methotrexate in patients with psoriatic arthritis.
机构信息
Division of Rheumatology, Allergy and Immunology, University of California San Diego, La Jolla, CA 92037-0943, USA.
出版信息
Clin Exp Rheumatol. 2010 Sep-Oct;28(5 Suppl 61):S132-7. Epub 2010 Oct 28.
PMID:21044447
Abstract
Despite a paucity of high quality clinical data, methotrexate (MTX) remains one of the most commonly used medications in the treatment of patients with psoriatic arthritis (PsA). This report addresses mechanistic rationale, available clinical evidence, safety considerations, and a potential research agenda regarding the use of MTX in the management of PsA.
摘要
尽管缺乏高质量的临床数据，但甲氨蝶呤（MTX）仍然是治疗银屑病关节炎（PsA）患者最常用的药物之一。本报告探讨了 MTX 在治疗 PsA 中的作用机制、现有临床证据、安全性考虑因素以及潜在的研究议程。
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