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[多发性硬化症中的编码过程与执行功能]

[Coding processes and executive functions in multiple sclerosis].

作者信息

Introzzi Isabel, Urquijo Sebastián, López Ramón María Fernanda

机构信息

Universidad Nacional de Mar de Plata/CONICET (Argentina), Facultad de Psicología, Mar del Plata, Argentina.

出版信息

Psicothema. 2010 Nov;22(4):684-90.

Abstract

Although episodic memory deficit in patients with multiple sclerosis (ME) is a well established fact, there is no agreement about the origin of this disorder in terms of cognitive processes. Whereas most of the studies attribute this deficit to defects in memory recovery processes, others contribute evidence in favor of the hypothesis that considers that it originates in difficulties in coding memory processes.However, the analysis of the relationship between coding processes and memory functioning in ME is a scantly studied topic. In the present article, we studied coding processes and their relationships with executive control processes in a group of patients with ME. We used a set of indexes of the Test of Verbal Learning from the TAVEC test for the evaluation of the coding processes. To assess the executive processes we used a semantic verbal fluency task, the WCST, and WAIS III scale of matrixes. We worked with 36 patients with ME diagnosis and 36 healthy control participants, paired by age and educational level. The results showed a deficit in the coding processes and the existence of a significant association between these processes and executive functioning.

摘要

尽管多发性硬化症(ME)患者存在情景记忆缺陷已是公认的事实,但就认知过程而言,对于这种障碍的起源尚无定论。大多数研究将这种缺陷归因于记忆恢复过程中的缺陷,而其他研究则提供证据支持认为其起源于编码记忆过程困难的假说。然而,对ME患者编码过程与记忆功能之间关系的分析是一个鲜有研究的课题。在本文中,我们研究了一组ME患者的编码过程及其与执行控制过程的关系。我们使用了TAVEC测试中言语学习测试的一组指标来评估编码过程。为了评估执行过程,我们使用了语义言语流畅性任务、威斯康星卡片分类测验(WCST)和韦氏成人智力量表第三版(WAIS III)矩阵量表。我们研究了36名确诊为ME的患者和36名健康对照参与者,他们在年龄和教育水平上进行了配对。结果显示编码过程存在缺陷,并且这些过程与执行功能之间存在显著关联。

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