Twetman Svante, Ekstrand Kim, Qvist Vibeke
Københavns Universitet, Det Sundhedsvidenskabelige Fakultet, Odontologisk Institut, Afdeling for Cariologi og Endodonti, København N, Denmark.
Ugeskr Laeger. 2010 Nov 1;172(44):3026-9.
Dental caries affects the majority of the Danish population. Its aetiology is multi-factorial, but a pH-induced change in the homeostasis of the oral biofilm leading to overgrowth of acid-tolerating bacteria is a key event. A non-invasive concept for prevention and management is emerging based on the common risk factor approach. There is strong evidence that tooth brushing twice a day with fluoridated toothpaste is the most cost-effective way to prevent and control caries development. Physicians need to consider that a number of drugs may affect the saliva flow rate, which increases the caries risk.
龋齿影响了大多数丹麦人。其病因是多因素的，但口腔生物膜内稳态因pH值变化导致耐酸细菌过度生长是一个关键事件。基于共同危险因素方法，一种预防和管理的非侵入性理念正在兴起。有强有力的证据表明，每天用含氟牙膏刷牙两次是预防和控制龋齿发展最具成本效益的方法。医生需要考虑到一些药物可能会影响唾液流速，从而增加龋齿风险。
