University of Cambridge, United Kingdom.
Arch Phys Med Rehabil. 2010 Nov;91(11):1637-40. doi: 10.1016/j.apmr.2010.05.017.
A clear, concise definition of traumatic brain injury (TBI) is fundamental for reporting, comparison, and interpretation of studies on TBI. Changing epidemiologic patterns, an increasing recognition of significance of mild TBI, and a better understanding of the subtler neurocognitive neuroaffective deficits that may result from these injuries make this need even more critical. The Demographics and Clinical Assessment Working Group of the International and Interagency Initiative toward Common Data Elements for Research on Traumatic Brain Injury and Psychological Health has therefore formed an expert group that proposes the following definition: In this article, we discuss criteria for considering or establishing a diagnosis of TBI, with a particular focus on the problems how a diagnosis of TBI can be made when patients present late after injury and how mild TBI may be differentiated from non-TBI causes with similar symptoms. Technologic advances in magnetic resonance imaging and the development of biomarkers offer potential for improving diagnostic accuracy in these situations.
颅脑创伤（TBI）的明确、简洁定义对于 TBI 研究的报告、比较和解释至关重要。不断变化的流行病学模式、对轻度 TBI 重要性的认识不断提高，以及对这些损伤可能导致的更微妙的神经认知神经情感缺陷的理解加深，使得这一需求更加关键。因此，国际和机构间创伤性脑损伤和心理健康研究共同数据元素倡议的人口统计学和临床评估工作组成立了一个专家组，提出了以下定义：在本文中，我们讨论了考虑或确立 TBI 诊断的标准，特别关注当患者在受伤后晚期就诊时如何做出 TBI 诊断，以及如何将轻度 TBI 与具有相似症状的非 TBI 原因区分开来。磁共振成像技术的进步和生物标志物的发展为改善这些情况下的诊断准确性提供了潜力。
